Results 71 to 80 of about 303,179 (311)
Clinical and Applied Thrombosis/Hemostasis, 2019 Cancer-associated thrombosis (CAT) studies have increased in recent years and the quality of guidelines to guide the clinical practice of CAT prevention and treatment becomes crucial.
Jiuxing Zhang BS +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Cat-associated sporotrichosis in humans caused by Sporothrix brasiliensis [PDF]
HEALTHCARE PROVIDERS: Emerging sporotrichosis is often spread by a bite or scratch from an infected cat and can have severe outcomes.CS311327-DSporothrix-brasiliensis-HCP-508 ...
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Asthma hospitalisations in Australia 2010-11 [PDF]
, 2013 This report provides an overview of asthma hospitalisation patterns over time and across population groups.SummaryAsthma is a common chronic condition of the airways, associated with episodes of wheezing, breathlessness, chest tightness and cough ...
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EXPERT SYSTEM FOR DIAGNOSING CAT DISEASES USING FORWARD CHAINING METHOD ON TELEGRAM BOT
, 2023 Cats are one of the popular pets kept in Indonesia. On the other hand, there is a potential risk of disease transmission from cats to humans. This research builds an expert system for diagnosing cat diseases based on the symptoms experienced using the ...
Ipung Permadi +3 more
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Microbiology Indonesia, 2014 Microbial resistance to antibiotic is a major problem in the treatment of infectious diseases. The purpose ofthis study was to identification the role of CAT enzyme for early detection of chloramphenicol resistant.
doaj +1 more source
Validation of the Medonic CA620/530 Vet 20-ml microcapillary sampler system for hematology testing of feline blood [PDF]
, 2009 The aim of the current study was to compare feline hematologic variables in blood collected in microcapillary tubes (20 ml) and conventional blood tubes with the Medonic CA620/530 Vet in-house hematologic analyzer.
Geffré, Anne +4 more
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