Results 91 to 100 of about 3,408,163 (311)

CAT booking office, Tainan

open access: yes, 2008
CAT booking office ...

core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Loading of CAT aircraft

open access: yes, 2008
Loading of CAT ...

core  

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Assessing health status in COPD. A head-to-head comparison between the COPD assessment test (CAT) and the clinical COPD questionnaire (CCQ)

open access: yesBMC Pulmonary Medicine, 2012
Background Health status provides valuable information, complementary to spirometry and improvement of health status has become an important treatment goal in COPD management.
Tsiligianni Ioanna G   +7 more
doaj   +1 more source

Advancing In Vitro Tools for Oncologic Research in Cats and Dogs

open access: yesVeterinary Sciences
In vitro culture systems have advanced cancer biology, particularly through 2D and 3D tumor cultures. These have answered numerous scientific inquiries and propelled human oncologic research, with growing recognition of their potential to improve cancer treatment in companion animals, specifically cats and dogs.
Chang He, Sven Rottenberg
openaire   +3 more sources

In Vitro Critical Appraisal Tool (IV-CAT): Tool Development Protocol

open access: yes, 2018
This document presents the protocol for development of the In-Vitro Critical Appraisal Tool (IV-CAT), intended to help ensure comprehensive and exacting peer-review of in vitro toxicology studies, and contribute to improving the quality of published in vitro research.
de Vries, Rob, Whaley, Paul
openaire   +2 more sources

CAT employee club

open access: yes, 2008
CAT employee ...
King, R.R.
core  

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Enhancing ESP writing skills through the use of Termsoup: An exploratory study

open access: yesTechnology in Language Teaching & Learning
As technology becomes increasingly integrated into educational settings, computer-assisted translation (CAT) tools are gaining recognition as valuable aids in language learning.
Szu-Yu Ruby Chen
doaj   +1 more source

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