Results 41 to 50 of about 3,408,163 (311)

Psychometric analysis of clinical chronic obstructive pulmonary disease questionnaire and chronic obstructive pulmonary disease assessment test and its correlation with St. George respiratory questionnaire in chronic obstructive pulmonary disease patients

Indian Journal of Respiratory Care, 2022
Introduction: Chronic obstructive pulmonary disease (COPD) is a disease of respiratory airflow obstruction. There are >80 tools to measure various aspects of COPD patients' well-being.
Syed Aamir Ali, Hajera Saniya, Khaja Naseeruddin, Sabiha Naaz Sana, Talath Fatima, Syed Mahmood Ahmed, Aleemuddin Naveed Mohd, Ashfaq Hasan, Fahad Abdullah   +8 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Free and Open Source Software in language mediator education:The MINTRAD Project

Translation and Interpreting : the International Journal of Translation and Interpreting Research, 2013
The paper provides a description of the main objectives pursued and results obtained by the “Grupo de Estudos das Tecnoloxías Libres da Tradución (GETLT)”[1] during the implementation of the MINTRAD project focusing on the compilation of Free and Open ...
Marta Garcia-Gonzalez
doaj  

The Translation of TV Commercials. Degrees of Localisation

Linguaculture, 2018
The paper aims at featuring some current advertising trends and their effect upon the re-mapping of translation strategies. Addressing the field of advertising from a translation-oriented perspective, we seek to look into how TV commercials’ relocation ...
Diana Oțăt
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Vertalers en tolken met visuele beperking. Specifieke problemen en mogelijke oplossingen

Acta Universitatis Carolinae Philologica, 2019
Visually impaired translators and interpreters have to cope with various specific problems in their work. The progress of modern technology has simplified access to information sources for them, but has in contrast created new barriers, which make their ...
Michal Homola
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

To Study the Correlation of Chronic Obstructive Pulmonary Disease (COPD) Assessment Test, Clinical COPD Questionnaire, and BODE Index in Patients of Stable COPD

Assam Journal of Internal Medicine, 2022
Background: Chronic obstructive pulmonary disease (COPD) assessment has emerged as one of the most important parts of COPD treatment. Therefore, a thorough assessment of symptoms is necessary rather than just a measure of dyspnea.
Amanpreet Kaur, Amit Goyal, Naveen Pandhi   +2 more
doaj   +1 more source