Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis [PDF]
, 2018 Objectives: Cellular energy metabolism is important for the function of all tissues, including cartilage. Recent studies indicate that superficial and deep subpopulations of articular chondrocytes (ACs) have distinct metabolic profiles.
O\u27Keefe, Regis J +3 more
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Molecular processes underlying synergistic linuron mineralization in a triple-species bacterial consortium biofilm revealed by differential transcriptomics [PDF]
, 2018 The proteobacteria Variovorax sp. WDL1, Comamonas testosteroni WDL7, and Hyphomicrobium sulfonivorans WDL6 compose a triple-species consortium that synergistically degrades and grows on the phenylurea herbicide linuron.
Anders +52 more
core +2 more sources
Scientific Reports, 2017 Ortho-phenylphenol (OPP) is a fungicide contained in agro-industrial effluents produced by fruit-packaging plants. Within the frame of developing bio-strategies to detoxify these effluents, an OPP-degrading Sphingomonas haloaromaticamans strain was ...
Chiara Perruchon +9 more
doaj +1 more source
New Insights into rice pyrimidine catabolic enzymes
Frontiers in Plant Science, 2023 IntroductionRice is a primary global food source, and its production is affected by abiotic stress, caused by climate change and other factors. Recently, the pyrimidine reductive catabolic pathway, catalyzed by dihydropyrimidine dehydrogenase (DHPD ...
Andrea J. Lopez +5 more
doaj +1 more source
Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism. [PDF]
, 2017 Malignant transformation is often accompanied by significant metabolic changes. To identify drivers underlying these changes, we calculated metabolic flux states for the NCI60 cell line collection and correlated the variance between metabolic states of ...
Bordbar, Aarash +5 more
core +1 more source
Molecular Plant-Microbe Interactions, 1998 Rhizopines are nodule-specific compounds that confer an intraspecies competitive nodulation advantage to strains that can catabolize them. The rhizopine (3-O-methyl-scyllo-inosamine, 3-O-MSI) catabolic moc gene cluster mocCABRDE(F) in Rhizobium ...
Masoud Bahar +5 more
doaj +1 more source
Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia [PDF]
, 1984 A six-year-old girl with severe hypercholesterolemia and atherosclerosis had two defective genes at the low-density-lipoprotein (LDL) receptor locus, as determined by biochemical studies of cultured fibroblasts.
Cummings +9 more
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Genes of different catabolic pathways are coordinately regulated by Dal81 in Saccharomyces cerevisiae [PDF]
, 2015 Yeast can use a wide variety of nitrogen compounds. However, the ability to synthesize enzymes and permeases for catabolism of poor nitrogen sources is limited in the presence of a rich one.
Bermudez Moretti, Mariana +2 more
core +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
IL-1ß and BMPs - Interactive players of cartilage matrix degradation and regeneration [PDF]
European Cells & Materials, 2006 Intact human adult articular cartilage is central for the functioning of the articulating joints. This largely depends on the integrity of its extracellular matrix, given the high loading forces during movements in particular in the weight-bearing joints.
T Aigner, S Soeder, J Haag
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