Results 311 to 320 of about 495,173 (383)

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

Pathological Disulfide Bond Crosslinking: Molecular Insights into Amyloidogenesis and Diseases Progression

open access: yesChemBioChem, EarlyView.
This review explores pathological disulfide‐crosslinking as a key driver of amyloidogenic protein misfolding and aggregation. Oxidative and ER stress pathways contributing to disease progression are discussed and emerging therapeutic strategies targeting disulfide‐linked aggregates in neurodegenerative and systemic amyloid diseases are examined ...
Dong Min Kang   +4 more
wiley   +1 more source

Exposure Experiments to Test the Kinetic Stability of 5‐Hydroxymethylfurfural Oxidase (HMFO) in Different Reactor Environments

open access: yesChemCatChem, EarlyView.
Scaling beyond the laboratory exposes enzymes to new stresses. Exposure experiments reveal that dynamic gas‐liquid interfaces introduced by sparging or air entrainment during agitation are the main drivers of HMFO deactivation. Replacing bubbles with a membrane‐based bubble‐free aeration system dramatically enhances stability. These experiments provide
Amalie Vang Høst   +4 more
wiley   +1 more source

Rivalling Self‐Oxidation and Aldehyde Deformylation by a Dinuclear Copper(II)‐Superoxide Complex

open access: yesChemCatChem, EarlyView.
A dinuclear Cu2L2‐O2•− reactive intermediate stabilized by a tetradentate N3O ligand set is postulated to be at the origin of aldehyde deformylation via a Baeyer‐Villiger oxidation mechanism, while enabling a radical self‐oxidation cascade in the absence of the substrate.
Andrea Squarcina   +4 more
wiley   +1 more source

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