Results 171 to 180 of about 174,911 (328)

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

riboCIRC v2.0: an expanded resource for translatable CircRNAs. [PDF]

Nucleic Acids Res
Xu Y, Yang L, Tang Y, Wang Y, Wang H.
europepmc   +1 more source

Mammalogy Class 1994 Catalog - Michigan, New Mexico and Mexico

, 1994
Lisa A Hollis
openalex   +1 more source

Reviewer #2 (Public Review): Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations

, 2023
Lauterbur M. Elise, Cavassim Maria Izabel A., Gladstein Ariella L., G. Scott Graham, Pope Nathaniel S., Tsambos Georgia, Adrion Jeff, Belsare Saurabh, Biddanda Arjun, Caudill Victoria, Cury Jean, Echevarria Ignacio, Haller Benjamin C., Hasan Ahmed R., Huang Xin, Iasi Leonardo Nicola Martin, Noskova Ekaterina, Obšteter Jana, Pavinato Vitor Antonio Corrêa, Pearson Alice, Peede David, Perez Manolo F., Rodrigues Murillo F., Smith Chris C. R., Spence Jeffrey P., Teterina Anastasia, Tittes Silas, Per Unneberg, Vazquez Juan Manuel, Waples Ryan K., Wohns Anthony Wilder, Wong Yan, Baumdicker Franz, Cartwright Reed A., Gorjanc Gregor, Gutenkunst Ryan N., Jerome Kelleher, Kern Andrew D., Ragsdale Aaron P., Ralph Peter L., Schrider Daniel R., Gronau Ilan   +41 more
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Editorial: In-depth interpretation of critical genomic information related to the biosynthesis of key specialized (secondary) metabolism in medicinal plants. [PDF]

Front Plant Sci
Wang M, Guo X, Wang Z.
europepmc   +1 more source

New Mexico, Wisconsin, Minnesota, Michigan, South Carolina, Missouri 1994 Catalog

, 1994
Andrew Hawk
openalex   +1 more source

Newly purchased items in the SLUB catalog in 2022

, 2023
Donatus Herre
openalex   +1 more source

Remembering Bob Ellett

, 2013
Bordner, Georgianne
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source