Results 41 to 50 of about 115,502 (279)

Martino’s Fragments: a personal library and its emblematic story

open access: yesBibliothecae.it, 2023
The personal library of Martino Mario Moreno, a diplomat who worked in the Italian colonies and became a scholar of Semitic and Cushitic linguistics, as well as of Islam and Arabic literature, has undergone a troubled history, marked by the fate of the ...
Oscar Nalesini
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Evaluating a historical medical book collection

open access: yesJournal of the Medical Library Association, 2019
Background: After several years of storing a large number of historical medical books that had been weeded from the general collection, the University of New Mexico Health Sciences Library and Informatics Center developed a set of evaluation criteria to ...
Karen R. McElfresh, Robyn M. Gleasner
doaj   +1 more source

More Cataloging, More LibGuide [PDF]

open access: yes, 2012
The way I have unified the LGBTQ titles—all 700-odd of them—is by using a local information field in the catalog. Quick cataloging lesson for you non-librarians: when I talk about subject headings, for example Gay Culture, those go in a field designated ...
Leone, Hannah R.
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Dünyada ve Ülkemizde RDA’ya Geçiş

open access: yesTürk Kütüphaneciliği, 2022
Amaç: Bilgi kaynaklarının bibliyografik tanımlanmasının amacı, bilgi kaynaklarını, kurallarla erişim uçlarını belirlemek ve bu kaynakları kullanıcılara sunmaktır. RDA, günümüzde bu işlemleri yapabilecek yeni kurallar bütünüdür.
Mustafa Bayter
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Development of Cataloging Rules [PDF]

open access: yes, 1953
published or submitted for ...
Lubetzky, Seymour
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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