Results 21 to 30 of about 15,758 (267)

Data Curation through Catalogs: A Repository-Independent Model for Data Discovery

open access: yesJournal of eScience Librarianship, 2021
Institutional data repositories are the acknowledged gold standard for data curation platforms in academic libraries. But not every institution can sustain a repository, and not every dataset can be archived due to legal, ethical, or authorial ...
Helenmary Sheridan   +4 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Search for quasar pairs with Gaia astrometric data

open access: yesAstronomy & Astrophysics
Quasar pairs, a special subclass of galaxy pairs, are valuable in the investigation of quasar interaction and clustering, the coevolution between the two quasars’ host galaxies, and the growth of supermassive black holes, as well as the formation and ...
Chen Qihang   +7 more
doaj   +3 more sources

Evaluation of the b Maps on the Faults of the Major (M > 7) South California Earthquakes

open access: yesEarth and Space Science
We use the Godano et al. (2022, https://doi.org/10.1029/2021ea002205) method for evaluating the b maps of the faults associated with the largest earthquakes M ≥ 7.0 that occurred in California.
V. Convertito, A. Tramelli, C. Godano
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

The Effect of Next-Generation Catalogs on Catalogers and Cataloging Functions in Academic Libraries [PDF]

open access: yesCataloging & Classification Quarterly, 2011
Next-generation catalogs or discovery tools (NGCs) overlay existing bibliographic data and repackage it in displays that differ from the traditional catalog. Many implementations of NGCs have revealed errors, omissions, or inconsistencies in the underlying data that had not been apparent in the traditional catalog.
Susan C. Wynne, Martha J. Hanscom
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Gaia white dwarfs with infrared excess

open access: yesAstronomy & Astrophysics
Context. The presence of infrared (IR) excess flux observed in white dwarfs is related to the existence of debris disks or substellar companions. These systems provide important clues in studies of extrasolar planetary material and binary evolution ...
Murillo-Ojeda R.   +3 more
doaj   +1 more source

Russian Virtual Observatory: Data Sources

open access: yesOpen Astronomy, 2016
The purpose of this review is to analyze main directions of creation and functioning of major data sources developed by Russian astronomers or with their participation and to compare them with the worldwide trends in these fields. We discuss astronomical
Malkov O.   +12 more
doaj   +1 more source

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