Results 51 to 60 of about 165,609 (290)

The MUSE-Wide Survey: Survey Description and First Data Release [PDF]

, 2019
We present the MUSE-Wide survey, a blind, 3D spectroscopic survey in the CANDELS/GOODS-S and CANDELS/COSMOS regions. Each MUSE-Wide pointing has a depth of 1 hour and hence targets more extreme and more luminous objects over 10 times the area of the MUSE-
Bacon, R., Boogaard, L., Brinchman, J., Caruana, J., Diener, C., Enke, H., Herenz, E. C., Kerutt, J., Klar, J., Krajnović, D., Maseda, M., Nanayakkara, T., Richard, J., Saust, R., Schmidt, K. B., Steinmetz, M., Urrutia, T., Weilbacher, P. M., Werhahn, M., Wisotzki, L.   +19 more
core   +5 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

EROS light-curve database

Astronomy & Astrophysics
Context. The project called Expérience de Recherche d’Objets Sombres (EROS) carried out photometric surveys of dense stellar fields toward the Magellanic Clouds (LMC and SMC), the Galactic bulge and Galactic spiral arms in the period 1990-2003.
Afonso C., Albert J.-N., Ansari R., Aubourg E., Beaulieu J.-P., Blaineau T., Coutures C., Derue F., Glicenstein J.-F., Goldman B., Hamadache C., Lasserre T., Le Guillou L., Lesquoy E., Magneville C., Mansoux B., Moniez M., Palanque-Delabrouille N., Perdereau O., Rich J., Spiro M., Tisserand P.   +21 more
doaj   +1 more source

Machine Learning Etudes in Astrophysics: Selection Functions for Mock Cluster Catalogs

, 2015
Making mock simulated catalogs is an important component of astrophysical data analysis. Selection criteria for observed astronomical objects are often too complicated to be derived from first principles.
Alvarez, Marcelo, Bond, J. Richard, Hajian, Amir   +2 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Search for quasar pairs with Gaia astrometric data

Astronomy & Astrophysics
Quasar pairs, a special subclass of galaxy pairs, are valuable in the investigation of quasar interaction and clustering, the coevolution between the two quasars’ host galaxies, and the growth of supermassive black holes, as well as the formation and ...
Chen Qihang, Jing Liang, Zhu Xingyu, Fang Yue, He Zizhao, Deng Zhuojun, Xiang Cheng, Wu Jianghua   +7 more
doaj   +1 more source

A Technique to Derive Improved Proper Motions for Kepler Objects of Interest [PDF]

, 2014
We outline an approach yielding proper motions with higher precision than exists in present catalogs for a sample of stars in the Kepler field. To increase proper motion precision we combine first moment centroids of Kepler pixel data from a single ...
Benedict, G. Fritz, Cargile, Phillip A., Ciardi, David R., Tanner, Angelle M.   +3 more
core   +4 more sources

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Selection and characterisation of the M dwarf targets in the PLATO Input Catalogue

Astronomy & Astrophysics
Context. The aim of the European Space Agency’s PLAnetary Transits and Oscillations of Stars (PLATO) mission is to detect planets orbiting around dwarfs and subgiant stars with spectral type F5 or later, including M dwarfs. The PLATO Input Catalogue (PIC)
Prisinzano L., Montalto M., Piotto G., Marrese P. M., Marinoni S., Nascimbeni V., Granata V., Cabrera J., Belkacem K., Deleuil M., Gizon L., Goupil M. J., Pagano I., Pollacco D., Ragazzoni R., Rauer H., Udry S., Maldonado J., Micela G., Damiani F., Affer L., Altavilla G., Argiroffi C., Benatti S., Cassisi S., Claudi R., Desidera S., Fabrizio M., Flaccomio E., Heiter U., Lanza A. F., Maggio A., Malavolta L., Nardiello D., Ortolani S., Sozzetti A.   +35 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source