Results 21 to 30 of about 116,570 (278)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

All different, all equal: changing basic principles of the authority control

open access: yesKnjižnica, 2001
To enable the collocation function of the catalogue, the uniform heading was introduced by the Paris Principles, and later on became one of the key elements for the Universal Bibliographic Control project.
Zlata Dimec
doaj   +1 more source

The Ukrainian Kyrylytsia, Restored: An Automation Project for Adding the Cyrillic Fields to Ukrainian Records in OCLC WorldCat

open access: yesEast/West: Journal of Ukrainian Studies, 2021
This report from the field concerns a collaborative project which resulted in successfully adding the Cyrillic fields to about 30,000 Ukrainian bibliographic records in OCLC WorldCat, the world’s largest online catalogue.
Jenny Toves   +2 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Ephemera publications as legal deposit in National and University library, Slovenia

open access: yesKnjižnica, 2010
The Slovenian production of all categories of library resources has been considerably increased over the last decade and ephemera comprise a large portion of the national output. The article explores some definitions of ephemera especially those given in
Veronika Potočnik
doaj   +1 more source

Cleaning up the catalogue [PDF]

open access: yes, 2010
The London School of Economics wanted to remove cataloguing inconsistencies but the scale of the task was huge, and outsourcing to a specialist bibliographic services company proved only a partial solution.
Williams, Helen K. R.
core  

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Cataloguing older monographic publications in the National and university library: cataloguer’s experience

open access: yesKnjižnica, 2008
The article describes the practice of cataloguing older monographic publications in the National and University Library, Ljubljana, Slovenia. The specific characteristics of this material, modes of acquisition, processing and preservation are presented ...
Jasna Hrovat
doaj   +1 more source

Managing an arts institutional repository [PDF]

open access: yes, 2012
The article describes the background to UCA Research Online which originated from the Kultur project of 2007-2009 and then goes onto detail the management of the institutional repository at ...
Spalding, Mary-Anne
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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