Results 181 to 190 of about 1,452 (232)

The VCPIP1‐UBE3A Deubiquitination‐Ubiquitination Cascade Contributes to Castration‐Resistant Prostate Cancer Progression

Advanced Science, EarlyView.
VCIPIP1 emerges as a molecular link between protein stability and prostate cancer progression. By deubiquitinating and stabilizing UBE3A, VCIPIP1 promotes p53 degradation and progression to castration‐resistant prostate cancer. Elevated VCIPIP1 expression is associated with shorter castration‐resistant prostate cancer–free survival, highlighting the ...
Fei Lin, Wen‐Cai Zheng, Yi‐Qiu Wang, Bin Lin, Yun‐Zhi Lin, Dong‐Ning Chen, Xiao‐Dong Li, Xue‐Yi Xue, Yong Wei, Ning Xu   +9 more
wiley   +1 more source

Beyond the clipboard: data collection with GridScore NEXT. [PDF]

BMC Bioinformatics
Raubach S, Schreiber M, Hamilton R, McKenzie G, McCallum S, Kilian B, Humphries A, Nguyen LH, Quang TH, Singh A, Sharma S, Trinder S, Feser M, Shaw PD.   +13 more
europepmc   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

Proteomics for precision nutrition: current evidence and future directions. [PDF]

Curr Opin Clin Nutr Metab Care
Marino M, Del Bo' C, Riso P.
europepmc   +1 more source

NUB1 Regulates Muscle Atrophy in Lung Cancer Cachexia via NF‐κB Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Cancer‐associated cachexia (CAC) is a devastating multifactorial syndrome characterized by progressive skeletal muscle atrophy. Its mechanisms remain incompletely clarified, with limited effective therapeutic targets. NUB1, a negative regulator of ubiquitin‐like proteins mediating protein degradation, has not been fully elucidated in CAC ...
Yuqi Han, Yaru Xia, Weiquan Li, Jiaming Wu, Tiexi Yu, Diaoyi Tan, Daojia Miao, Wen Li, Xuejiao Dong, Jiemin Li, Yu Jiao, Guixiao Huang, Xiaoping Zhang, Hongmei Yang   +13 more
wiley   +1 more source

Molecular switches in cell death: the interplay of apoptosis and pyroptosis in cancer. [PDF]

Cell Commun Signal
Liu Y, Xie Y.
europepmc   +1 more source

Probiogenomics as a Computational Biotechnology Framework: Safety-Gated Genome Analytics for Candidate Probiotic Prioritization and Validation. [PDF]

Comput Struct Biotechnol J
Chaichana N, Surachat K.
europepmc   +1 more source

A machine learning driven automated system to extract multiple information fields from safety data sheet documents. [PDF]

Heliyon
Khan M, Penfield J, Suman A, Crowell S.
europepmc   +1 more source