Results 31 to 40 of about 1,637,694 (225)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Statement of International Cataloguing Principles 2009

, 2009
The Statement of Principles – commonly known as the “Paris Principles” – was approved by the International Conference on Cataloguing Principles in 1961.1 Its goal of serving as a basis for international standardization in cataloguing has certainly been ...
IFLA Meetings of Experts on an International Cataloguing Code, IFLA Cataloguing Section   +1 more
core   +2 more sources

Quo vadis Inhaltserschließung der Deutschen Nationalbibliothek? Herausforderungen und Perspektiven

o-bib. Das offene Bibliotheksjournal, 2015
Seit der Ausweitung des Pflichtexemplarrechts auf sog. unkörperliche Medienwerke im Jahr 2006 steht die Deutsche Nationalbibliothek (DNB) vor der Herausforderung, über neue Wege zur Erzeugung bibliografischer Metadaten nachzudenken.
Ulrike Junger
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Challenges for the Implementation of Resource Description and Access (RDA) Case Study Germany [PDF]

, 2008
At the “97th Bibliothekartag” in June 2008 Susanne Oehlschläger from the German National Library spoke about the implementation of the new standardisation system RDA in Germany. As early as 2011 RDA will replace the German cataloguing standard “Rules for
Eichel, Dierk, Caesar, Ingo
core   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

The status of photographs as library materials and their cataloguing through the perspective of Slovenian handbooks, reg

Knjižnica, 2004
The article presents an overview of Slovene handbooks, regulations and standards, which are, or have been, used in the cataloguing of library materials. The research is concentrated on their relation with photographic materials ie. with the smallest part,
Branka Kerec
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Manus OnLine and the Text Encoding Initiative Schema

Journal of the Text Encoding Initiative, 2014
The Italian Central Institute of Cataloguing (ICCU) has developed a web application to export manuscript descriptions from Manus OnLine (MOL), the Italian national catalogue of manuscripts, into TEI XML documents. As of June 2013, single descriptions can
Giliola Barbero, Francesca Trasselli
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source