Results 11 to 20 of about 238,554 (268)

Cohort study evaluating the burden of wounds to the UK’s National Health Service in 2017/2018: update from 2012/2013

open access: yesBMJ Open, 2020
Objective To evaluate the prevalence of wounds managed by the UK’s National Health Service (NHS) in 2017/2018 and associated health outcomes, resource use and costs.Design Retrospective cohort analysis of the electronic records of patients from The ...
Julian F Guest   +2 more
doaj   +1 more source

DNA Hybridization Catalysts and Catalyst Circuits [PDF]

open access: yes, 2005
Practically all of life's molecular processes, from chemical synthesis to replication, involve enzymes that carry out their functions through the catalysis of metastable fuels into waste products. Catalytic control of reaction rates will prove to be as useful and ubiquitous in DNA nanotechnology as it is in biology. Here we present experimental results
Georg Seelig   +2 more
openaire   +2 more sources

A catalyst for change [PDF]

open access: yesCanadian Medical Association Journal, 2006
The Journal's Editor in Chief, John Hoey, and Senior Deputy Editor, Anne Marie Todkill, were dismissed on Feb. 20, 2006. Their departure is a blow to the CMAJ , Canadian physicians and the international scientific and medical communities.
Stephen, Choi   +6 more
openaire   +2 more sources

A catalyst for change [PDF]

open access: yesEye, 2020
NHS long term plan. 2019. https://www.longtermplan.nhs.uk/. Accessed August 2020. NHS Digital. Hospital Episode Statistics – Outpatient and Admitted Patient Care 2010–2019. https://digital.nhs.uk/data-and-information/data-tools-and-services/data-services/hospital-episode-statistics. Accessed August 2020.
Parul Desai, David Parkins, Zoe Richmond
openaire   +2 more sources

Small-Format Drug Conjugates: A Viable Alternative to ADCs for Solid Tumours?

open access: yesAntibodies, 2018
Antibody–Drug Conjugates (ADCs) have been through multiple cycles of technological innovation since the concept was first practically demonstrated ~40 years ago.
Mahendra P. Deonarain   +7 more
doaj   +1 more source

Living with tuberculosis: a qualitative study of patients’ experiences with disease and treatment

open access: yesBMC Public Health, 2022
Background Although tuberculosis (TB) is a curable disease, treatment is complex and prolonged, requiring considerable commitment from patients. This study aimed to understand the common perspectives of TB patients across Brazil, Russia, India, China ...
Juliet Addo   +7 more
doaj   +1 more source

Meso-Structuring of SiCN Ceramics by Polystyrene Templates

open access: yesNanomaterials, 2015
A simple one-pot synthesis of well-defined PS-silazane nano-composites (polystyrene, PS) is described. In contrast to the, thus far, used two-step procedure ((1) assembly of a PS template bed and (2) careful filling of the voids between the PS spheres),
Julia-Katharina Ewert   +4 more
doaj   +1 more source

Adoptive cell therapy with tumour-infiltrating lymphocytes: the emerging importance of clonal neoantigen targets for next-generation products in non-small cell lung cancer

open access: yesImmuno-Oncology and Technology, 2019
Immune checkpoint blockade has significantly improved clinical outcomes for patients with non-small cell lung cancer (NSCLC) and other solid tumours, but many patients do not respond and acquired resistance is common.
Jane Robertson, Max Salm, Markus Dangl
doaj   +1 more source

Thermodynamic principle to enhance enzymatic activity using the substrate affinity

open access: yesNature Communications, 2023
Understanding how to tune enzymatic activity is important not only for biotechnological applications, but also to elucidate the basic principles guiding the design and optimization of biological systems in nature.
Hideshi Ooka   +2 more
doaj   +1 more source

Cohort study to characterise surgical site infections after open surgery in the UK’s National Health Service

open access: yesBMJ Open, 2023
Objective To characterise surgical site infections (SSIs) after open surgery in the UK’s National Health Service.Design Retrospective cohort analysis of electronic records of patients from Clinical Practice Research Datalink, linked with Hospital Episode
Julian F Guest   +2 more
doaj   +1 more source

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