Results 41 to 50 of about 238,554 (268)

Efficient catalytic removal of COS and H2S over graphitized 2D micro-meso-macroporous carbons endowed with ample nitrogen sites synthesized via mechanochemical carbonization

Green Energy & Environment, 2022
Developing a suitable catalyst for the elimination of highly toxic carbonyl sulfide (COS) and hydrogen sulfide (H2S) is of great significance in terms of industrial safety and environmental protection.
Xun Kan, Guanqing Zhang, Yingying Luo, Fujian Liu, Yong Zheng, Yihong Xiao, Yanning Cao, Chak-tong Au, Shijing Liang, Lilong Jiang   +9 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Nitrogen- and Halogen-Free Multifunctional Polymer-Directed Fabrication of Aluminum-Rich Hierarchical MFI Zeolites

Nanomaterials, 2022
Aluminum-rich hierarchical MFI-type zeolites with high acidic-site density exhibit excellent activity and selectivity in bulky molecule-involved reactions.
Yuan Hu, Chan Wang, Tiesen Li, Xiaojun Bao, Yuanyuan Yue   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Sun Protection Products Protect Against UV-Induced Mitochondrial DNA Damage and Blue Light-Induced Cell Decline in Human Dermal Fibroblast Skin Cell Viability

Cosmetics
The first part of the study shows that four commercial sun protection SPF 50 products provide statistically significant (all p < 0.021) protection by reducing the amount of UV-induced mitochondrial (mtDNA) damage in human dermal fibroblast skin cells (i ...
Jessica Moor, Amy Bowman, Hina Choudhary, Jonathan Brookes, Patricia Brieva, Mark Anthony Birch-Machin   +5 more
doaj   +1 more source

Alkaline-Earth Metals-Doped Pyrochlore Gd2Zr2O7 as Oxygen Conductors for Improved NO2 Sensing Performance

Scientific Reports, 2017
This work proposed a novel strategy to fabricate highly-stable NO2 sensor based on a pyrochlore-phase Gd2Zr2O7 oxygen conductor. The incorporation of alkaline-earth metals distinctly enhances the sensing performance of the Gd2Zr2O7 based sensors.
Fulan Zhong, Jiwu Zhao, Lanqian Shi, Yihong Xiao, Guohui Cai, Yong Zheng, Jinlin Long   +6 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

An Asymmetric Catalyst.

Nippon kagaku zassi, 1956
ASYMMETRIC synthesis has hitherto succeeded only by using reagents or solvents having the asymmetric configuration.
S. AKABORI, S. SAKURAI, Y. IZUMI, Y. FUJII   +3 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source