Results 21 to 30 of about 1,701,099 (359)

Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug

open access: yesCPT: Pharmacometrics & Systems Pharmacology, 2022
Marzeptacog alfa (activated) (MarzAA) is an activated recombinant human FVII (rFVIIa) variant developed as subcutaneous (s.c.) administration for the treatment or prevention of bleeding episodes in patients with hemophilia A (HA) or hemophilia B (HB ...
Alan Faraj   +5 more
doaj   +1 more source

Cohort study evaluating the burden of wounds to the UK’s National Health Service in 2017/2018: update from 2012/2013

open access: yesBMJ Open, 2020
Objective To evaluate the prevalence of wounds managed by the UK’s National Health Service (NHS) in 2017/2018 and associated health outcomes, resource use and costs.Design Retrospective cohort analysis of the electronic records of patients from The ...
Julian F Guest   +2 more
doaj   +1 more source

Living with tuberculosis: a qualitative study of patients’ experiences with disease and treatment

open access: yesBMC Public Health, 2022
Background Although tuberculosis (TB) is a curable disease, treatment is complex and prolonged, requiring considerable commitment from patients. This study aimed to understand the common perspectives of TB patients across Brazil, Russia, India, China ...
Juliet Addo   +7 more
doaj   +1 more source

A catalyst for change [PDF]

open access: yeseLife, 2021
Disillusioned with conducting chemistry experiments in a basement, a new graduate student decides instead to dedicate her PhD to improving the culture of her research environment.
openaire   +3 more sources

Small-Format Drug Conjugates: A Viable Alternative to ADCs for Solid Tumours?

open access: yesAntibodies, 2018
Antibody–Drug Conjugates (ADCs) have been through multiple cycles of technological innovation since the concept was first practically demonstrated ~40 years ago.
Mahendra P. Deonarain   +7 more
doaj   +1 more source

Meso-Structuring of SiCN Ceramics by Polystyrene Templates

open access: yesNanomaterials, 2015
A simple one-pot synthesis of well-defined PS-silazane nano-composites (polystyrene, PS) is described. In contrast to the, thus far, used two-step procedure ((1) assembly of a PS template bed and (2) careful filling of the voids between the PS spheres),
Julia-Katharina Ewert   +4 more
doaj   +1 more source

Adoptive cell therapy with tumour-infiltrating lymphocytes: the emerging importance of clonal neoantigen targets for next-generation products in non-small cell lung cancer

open access: yesImmuno-Oncology and Technology, 2019
Immune checkpoint blockade has significantly improved clinical outcomes for patients with non-small cell lung cancer (NSCLC) and other solid tumours, but many patients do not respond and acquired resistance is common.
Jane Robertson, Max Salm, Markus Dangl
doaj   +1 more source

Effect of Catalyst and Catalyst Layer Composition on Catalyst Support Durability

open access: yesJournal of The Electrochemical Society, 2021
Polymer electrolyte membrane fuel cells (PEMFCs) are efficient, zero-emission engines for the automotive sector. However, cost and durability are major barriers for the commercialization of PEMFCs. Degradation of the carbon support in the cathode catalyst layer due to high potential excursions caused by unmitigated events like H2 starvation, or start ...
Siddharth Komini Babu   +9 more
openaire   +1 more source

Iodide Adsorption from Water and Wastewater Using a Selective Hydrated Zr (IV) Oxide Particle-Impregnated Anion Exchange Resin; Batch and Column Studies [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2023
Water pollution by iodo-compounds such as iodide ions is known as a vital issue due to its detrimental effect on human health. In the present study, hydrated zirconium oxide particle (HZO)-impregnated anion exchange resin, was synthesized for selective ...
Mona Akbari, Shahram Sharifnia
doaj   +1 more source

Carbene Catalysts [PDF]

open access: yes, 2009
The use of N-heterocyclic carbenes as catalysts for organic transformations has received increased attention in the past 10 years. A discussion of catalyst development and nucleophilic characteristics precedes a description of recent advancements and new reactions using N-heterocyclic carbenes in catalysis.
Jennifer L, Moore, Tomislav, Rovis
openaire   +2 more sources

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