Results 71 to 80 of about 238,554 (268)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Recovery of Iodine as Triiodide by Strongly Basic Anion Exchange Resins; Development of Chromatographic Method [PDF]

Iranian Journal of Chemistry & Chemical Engineering
The present study outlines a general process to recover iodine from brine water or wastewater by strongly basic anion exchange resins. At first, iodide anions were oxidized to iodine or triiodide (the appropriate amount of H2O2 and HCl was added to the ...
Shahram Sharifnia, Mona Akbari
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

A Novel Highly Sensitive NO2 Sensor Based on Perovskite Na0.5+xBi0.5TiO3−δ Electrolyte

Scientific Reports, 2017
NOx is one of dangerous air pollutants, and the demands for reliable sensors to detect NOx are extremely urgent recently. Conventional fluorite-phase YSZ used for NOx sensor requires higher operating temperature to obtain desirable oxygen ion ...
Yihong Xiao, Chufan Zhang, Xu Zhang, Guohui Cai, Yong Zheng, Ying Zheng, Fulan Zhong, Lilong Jiang   +7 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Stress corrosion cracking behavior of pipeline steel due to liquid ammonia with water and oxygen impurities

You-qi chuyun
ObjectiveClassified as a high-strength low-alloy steel, pipeline steel is suitable for large-scale, long-distance pipeline transportation of liquid ammonia.
Jiaqing LI, Huilong LIANG, Zhiyu FENG, Pengbo YIN, Lin TENG, Zhuwu ZHANG, Yu LUO, Lilong JIANG   +7 more
doaj   +1 more source

Biodiesel production using alkali earth metal oxides catalysts synthesized by sol-gel method [PDF]

Biofuel Research Journal, 2014
Biodiesel fuel is considered as an alternative to diesel fuel. This fuel is produced through transesterification reactions of vegetable oils or animal fat by alcohols in the presence of different catalysts. Recent studies on this process have shown that,
Majid Mohadesi, Zahra Hojabri, Gholamreza Moradi   +2 more
doaj  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Rational design of deep eutectic solvents with low viscosities and multiple active sites for efficient recognition and selective capture of NH3

Smart Molecules
Efficient recognition and selective capture of NH3 is not only beneficial for increasing the productivity of the synthetic NH3 industry but also for reducing air pollution. For this purpose, a group of deep eutectic solvents (DESs) consisting of glycolic
Lu Zheng, Saisai Ju, Siqi Fang, Hongwei Zhang, Zhenping Cai, Kuan Huang, Lilong Jiang   +6 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source