Results 71 to 80 of about 484,835 (289)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Bimetallic Single-Atom Catalysts for Electrocatalytic and Photocatalytic Hydrogen Production

, 2023
Electrocatalytic and photocatalytic hydrogen evolution reactions (HERs) provide a promising approach to clean energy generation. Bimetallic single-atom catalysts have been developed and explored to be advanced catalysts for HER.
Dafeng Yan, Mengyang Zhang, Ning Sun, Yanling Zhuang, Keyu Xu, Longlu Wang   +5 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Efficient in-situ synthesis of heterocyclic derivatives from benzyl alcohols using pyrazinium chlorochromate-functionalized carbonitride as a novel catalyst

Scientific Reports
The synthesis of efficient organic compounds from simple substrates is both noticeable and important. However, it can be challenging to achieve this target using suitable strategies.
Hasan Soltani, Zeinab Tajik, Zahra Nasri, Peyman Hanifehnejad, Elaheh Hamidi, Zahra Aslbeigi, Hossein Ghafuri   +6 more
doaj   +1 more source

DNA Hybridization Catalysts and Catalyst Circuits [PDF]

, 2005
Practically all of life's molecular processes, from chemical synthesis to replication, involve enzymes that carry out their functions through the catalysis of metastable fuels into waste products. Catalytic control of reaction rates will prove to be as useful and ubiquitous in DNA nanotechnology as it is in biology. Here we present experimental results
Georg Seelig, Bernard Yurke, Erik Winfree   +2 more
openaire   +3 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Reflectivity of Photonic Crystals Self-assembled with Silica Spheres

Journal of Thermal Science and Technology, 2006
We investigate the spectral reflectivity of photonic crystals assembled with silica spheres. The propagation of electromagnetic wave can be controlled by periodic structures known as photonic crystals.
Masahiro KIHARA, Koji MIYAZAKI, Hiroshi TSUKAMOTO, Kazuaki INOUE, Osamu YOSHIDA   +4 more
doaj   +1 more source

Acknowledgement to Reviewers of Catalysts in 2015

, 2016
The editors of Catalysts would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015.
Catalysts Editorial Office
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source