Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
A model for propagation of RNA structural memory through biomolecular condensates. [PDF]
Cai C, Yu J, Zhang X, Zhou T, Chen Q.
europepmc +1 more source
Functional dissection of H3K4 methyltransferases reveals distinct catalytic and non-catalytic roles in C. elegans development. [PDF]
Attianese B +6 more
europepmc +1 more source
Discovering, Integrating, and Reinterpreting the Molecular Logic of Life: From Classical Theories of Heredity to an Extended Functional Perspective on the Central Dogma. [PDF]
Grădinaru AC.
europepmc +1 more source
An N-terminal helix of Lsm11 stabilizes CPSF73 in U7 snRNP for histone pre-mRNA 3'-end processing. [PDF]
Desotell A +3 more
europepmc +1 more source
Incorporation of arabinose-CTP and arabinose-UTP inhibits viral polymerases by inducing long pauses. [PDF]
Xiao Z +7 more
europepmc +1 more source
Generative inverse design of RNA structure and function with gRNAde
Joshi CK +5 more
europepmc +1 more source

