Results 41 to 50 of about 260,075 (308)

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Photothermal Transport for Guiding Nanoparticles Through the Vitreous Humor

Advanced Science, EarlyView.
Nanosecond laser irradiation of the clinically approved dye indocyanine green (ICG) enables light‐guided nanoparticle transport within the vitreous humor. The combined use of ICG and pulsed laser illumination induces localized convection and thermophoresis, directing particles toward illuminated regions.
Léa Guerassimoff, Yera Ussembayev, Louise De Clerck, Deep Punj, Martijn van den Broek, Filip Beunis, Katrien Remaut, Kevin Braeckmans, Stefaan C. De Smedt, Félix Sauvage   +9 more
wiley   +1 more source

Pharmacological Therapy for Presbyopia in Patients with Previous Corneal Refractive Surgery: A Pilot Study

Ophthalmology and Therapy, 2020
Purpose To perform a pilot evaluation of a novel pharmacological therapy for presbyopia in patients with previous corneal refractive surgery. Methods This interventional study included 130 presbyopic patients. The patients were divided into three groups:
Veronica Vargas, Felipe Vejarano, Jorge Alió   +2 more
doaj   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Promising Pharmacological Interventions for Posterior Capsule Opacification: A Review

Global Challenges
Phacoemulsification combined with intraocular lens implantation is the primary treatment for cataract. Although this treatment strategy benefits patients with cataracts, posterior capsule opacification (PCO) remains a common complication that impairs ...
Yuxuan Liu, Xiaoming Dong, Bin Wu, Zhigang Cheng, Jinsong Zhang, Jing Wang   +5 more
doaj   +1 more source

Cellular therapy of the corneal stroma: a new type of corneal surgery for keratoconus and corneal dystrophies

Eye and Vision, 2018
Cellular therapy of the corneal stroma, with either ocular or extraocular stem cells, has been gaining a lot of interest over the last decade. Multiple publications from different research groups are showing its potential benefits in relation to its ...
Jorge L. Alió del Barrio, Jorge L. Alió   +1 more
doaj   +1 more source

Risk Factors and Incidence of Macular Edema after Cataract Surgery: A Database Study of 81984 Eyes.

Ophthalmology (Rochester, Minn.), 2016
PURPOSE To define the incidence of pseudophakic macular edema (PME) after cataract surgery and to identify contributory risk factors. DESIGN Retrospective database study of electronic medical records (EMRs).
Colin J. Chu, R. Johnston, Charlotte P Buscombe, A. Sallam, Q. Mohamed, Y. C. Yang   +5 more
semanticscholar   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

Advanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang, Wen Zhou, Haotian Xue, Wenjun Xue, Guangping Gao, Bing Zhu, Hongyuan Song, Qingqiang Xu, Jing Zhao, Wei Shen   +9 more
wiley   +1 more source

Biodegradable and Bioinspired UV Light Recognition via Sustainable Synaptic Transistors for Artificial Intelligence Vision Systems

Advanced Intelligent Systems, EarlyView.
We report a biodegradable electrolyte‐gated synaptic phototransistor that combines low‐power UV sensing with memory functionality, offering a sustainable platform for AI vision systems and health‐monitoring technologies. Presented here is a biodegradable, bioinspired synaptic phototransistor (SPT) based on an electrolyte‐gated field‐effect transistor ...
Theodoros Serghiou, Rogério Morais, Douglas Henrique Vieira, Neri Alves, Roghaieh Parvizi, Jeff Kettle   +5 more
wiley   +1 more source

Comparisons of biometric parameters measurements by OPD-SCAN Ⅲ and Pentacam in cataract

Photodiagnosis and Photodynamic Therapy
Background: Comparison of OPD-Scan III and Pentacam measurements of relevant parameters guiding the selection of multifocal intraocular lenses in cataract patients. Methods: A retrospective study included 120 patients (120 eyes) with cataract.
Shiqi Dong, Rong Xu, Yue Wang, Wei Xiao, Ya Jiao   +4 more
doaj   +1 more source