Results 41 to 50 of about 306,109 (303)

Nationwide Characterization of MFN2‐Related CMT in 176 Japanese Patients: Clinical and Genetic Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Mitofusin 2 (MFN2) is a major causative gene for axonal Charcot – Marie – Tooth disease type 2A (CMT2A), with a wide phenotypic spectrum. Comprehensive large ‐ scale genotype – phenotype association studies are essential for understanding disease pathogenesis and improved clinical management.
Masahiro Ando, Yujiro Higuchi, Jun‐Hui Yuan, Akiko Yoshimura, Chikashi Yano, Takahiro Hobara, Fumikazu Kojima, Yu Hiramatsu, Satoshi Nozuma, Tomonori Nakamura, Yusuke Sakiyama, Jun Mitsui, Shoji Tsuji, Hiroshi Takashima   +13 more
wiley   +1 more source

Promising Pharmacological Interventions for Posterior Capsule Opacification: A Review

Global Challenges
Phacoemulsification combined with intraocular lens implantation is the primary treatment for cataract. Although this treatment strategy benefits patients with cataracts, posterior capsule opacification (PCO) remains a common complication that impairs ...
Yuxuan Liu, Xiaoming Dong, Bin Wu, Zhigang Cheng, Jinsong Zhang, Jing Wang   +5 more
doaj   +1 more source

Ocular biometric parameters associated with the performance of actual near-add power in multifocal intraocular lenses [PDF]

International Journal of Ophthalmology
AIM: To evaluate the influence of ocular biometric parameters on the performance of actual near-add power in the spectacle plane of multifocal intraocular lenses (MIOLs).
Ying-Feng Hu, Yan Wang, Rong Zhang, Zheng Wang, Xiang-Yu Ye   +4 more
doaj   +1 more source

Hydrogen peroxide enhances transforming growth factor beta-2 induced epithelial–mesenchymal transition of ARPE-19 cells

Beni-Suef University Journal of Basic and Applied Sciences, 2023
Background In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico ...
Brijesh Gelat, Pooja Rathaur, Pooja Malaviya, Binita Patel, Abhay R. Vasavada, S. R. Kaid Johar   +5 more
doaj   +1 more source

Economic inequalities in burden of illness, diagnosis and treatment of five long-term conditions in England: panel study [PDF]

, 2014
We compared the distribution by wealth of self-reported illness burden (estimated from validated scales, biomarker and reported symptoms) for angina, cataract, depression, diabetes and osteoarthritis, with the distribution of self-reported medical ...
Bachmann, M. O., Campbell, J., Clark, A., Hardcastle, A. C., Lang, I., Melzer, D., Mounce, L. T. A., Richards, S. H., Steel, N.   +8 more
core   +2 more sources

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew, Maryam Kargaran, Maik Rothe, Andreas Deistung, Dietrich Stoevesandt, Walter A. Wohlgemuth, David Strube, Thomas Kendzierski, Anna Katharina Kölsch, Maurits Gerhard Abraham Heuschen, Markus Otto, Alexander Mensch   +11 more
wiley   +1 more source

Advanced Oral Delivery Systems for Nutraceuticals

Advanced Healthcare Materials, EarlyView.
Emerging delivery technologies are explored to overcome barriers to oral nutraceutical absorption. Traditional carriers are compared with novel platforms including biodegradable polymers, MOFs, MPNs, and 3D printing. These systems enhance bioavailability, control release, and enable personalized nutrition.
Xin Yang, Linzixuan Zhang, Zhiling Zheng, Robert Langer, Ana Jaklenec   +4 more
wiley   +1 more source

Comparisons of biometric parameters measurements by OPD-SCAN Ⅲ and Pentacam in cataract

Photodiagnosis and Photodynamic Therapy
Background: Comparison of OPD-Scan III and Pentacam measurements of relevant parameters guiding the selection of multifocal intraocular lenses in cataract patients. Methods: A retrospective study included 120 patients (120 eyes) with cataract.
Shiqi Dong, Rong Xu, Yue Wang, Wei Xiao, Ya Jiao   +4 more
doaj   +1 more source

First clinical case series of frosted branch angiitis: A diagnostic algorithm is suggested

Clinical Case Reports, 2023
Key Clinical Message FBA is a clinical diagnosis of a diverse spectrum, which needs a high index of suspicion to identify the possible specific etiologies. The zones of retinal involvement can help in predicting the final visual outcome.
Bharat Gurnani, Sivaraman Balamurugan, Anuradha Kanakath, Kirandeep Kaur, Abhay Gupta, Sameer Chaudhary   +5 more
doaj   +1 more source

Canaloplasty in the Treatment of Open-Angle Glaucoma: A Review of Patient Selection and Outcomes. [PDF]

, 2018
Canaloplasty is a relatively new non-penetrating surgery for the reduction of intraocular pressure in patients affected by glaucoma. The technique uses a microcatheter to perform a 360 º cannulation of Schlemm's canal and leaves in place a tension suture
Brusini, Paolo, Michelessi, Manuele, Oddone, Francesco, Quaranta, Luciano, Riva, Ivano, Weinreb, Robert N   +5 more
core   +2 more sources