Results 1 to 10 of about 54,030 (246)
Nature Reviews Disease Primers, 2015 Cataract is the leading cause of reversible blindness and visual impairment globally. Blindness from cataract is more common in populations with low socioeconomic status and in developing countries than in developed countries. The only treatment for cataract is surgery.
Lam, Dennis +9 more
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Cells, 2023 Defects in the development of the ocular lens can cause congenital cataracts. To understand the various etiologies of congenital cataracts, it is important to characterize the genes linked to this developmental defect and to define their downstream ...
Archana D. Siddam +8 more
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Autophagy in the eye: from physiology to pathophysiology
Autophagy Reports, 2023 Autophagy is a catabolic self-degradative pathway that promotes the degradation and recycling of intracellular material through the lysosomal compartment. Although first believed to function in conditions of nutritional stress, autophagy is emerging as a
Paloma B. Liton +15 more
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American Journal of Ophthalmology Case Reports, 2020 Purpose: To describe two cases of ectopia lentis with different preoperative management strategies following the initial diagnostic dilated exam. Observations: In both cases, the patients presented with bilateral subluxation of the crystalline lens ...
William Plum +5 more
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Journal of Ageing and Longevity, 2023 The global incidence of dementia has been rising for the past several years, posing significant health challenges regarding its management and prevention. Dementia is associated with a substantial burden on patients and their families.
Yoh Tamaki +2 more
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Zinc and Copper Ions Induce Aggregation of Human β-Crystallins
Molecules, 2022 Cataracts are defined as the clouding of the lens due to the formation of insoluble protein aggregates. Metal ions exposure has been recognized as a risk factor in the cataract formation process. The γ and β crystallins are members of a larger family and
Vanesa Ramirez-Bello +3 more
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Cataracts are Associated with the Coexistence of Moderate to Severe Obstructive Sleep Apnea and Diabetes Mellitus [PDF]
Sleep Medicine Research, 2020 Background and Objective The individual presence of diabetes mellitus (DM) or obstructive sleep apnea (OSA) is significantly associated with cataract formation, but few studies have examined the association of cataracts with comorbid DM and OSA.
Seungku Lee +4 more
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Indian Journal of Ophthalmology, 2022 Purpose: To determine the prevalence and risk factors for cataracts in the Vientiane Province. Methods: We conducted a population-based study of 1264 participants aged ≥40 years of age from urban and rural areas of Vientiane Province.
Brad Guo +6 more
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Cataract and surgery for cataract [PDF]
BMJ, 2006 Cataract surgery is the commonest single surgical procedure carried out in the developed world. In the developing world, cataract remains the commonest cause of blindness. In 1990 an estimated 37 million people were blind worldwide—40% of them because of cataract.1 Every year, an extra 1-2 million people go blind.
David, Allen, Abhay, Vasavada
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Connexin Mutants Cause Cataracts Through Deposition of Apatite
Frontiers in Cell and Developmental Biology, 2022 Cataracts are lens opacities that are among the most common causes of blindness. It is commonly believed that cataracts develop through the accumulation of damage to lens proteins.
Peter J. Minogue +5 more
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