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Defects in the development of the ocular lens can cause congenital cataracts. To understand the various etiologies of congenital cataracts, it is important to characterize the genes linked to this developmental defect and to define their downstream ...
Archana D. Siddam +8 more
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Autophagy in the eye: from physiology to pathophysiology
Autophagy is a catabolic self-degradative pathway that promotes the degradation and recycling of intracellular material through the lysosomal compartment. Although first believed to function in conditions of nutritional stress, autophagy is emerging as a
Paloma B. Liton +15 more
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The global incidence of dementia has been rising for the past several years, posing significant health challenges regarding its management and prevention. Dementia is associated with a substantial burden on patients and their families.
Yoh Tamaki +2 more
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Zinc and Copper Ions Induce Aggregation of Human β-Crystallins
Cataracts are defined as the clouding of the lens due to the formation of insoluble protein aggregates. Metal ions exposure has been recognized as a risk factor in the cataract formation process. The γ and β crystallins are members of a larger family and
Vanesa Ramirez-Bello +3 more
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Purpose: To describe two cases of ectopia lentis with different preoperative management strategies following the initial diagnostic dilated exam. Observations: In both cases, the patients presented with bilateral subluxation of the crystalline lens ...
William Plum +5 more
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Cataracts are Associated with the Coexistence of Moderate to Severe Obstructive Sleep Apnea and Diabetes Mellitus [PDF]
Background and Objective The individual presence of diabetes mellitus (DM) or obstructive sleep apnea (OSA) is significantly associated with cataract formation, but few studies have examined the association of cataracts with comorbid DM and OSA.
Seungku Lee +4 more
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Purpose: To determine the prevalence and risk factors for cataracts in the Vientiane Province. Methods: We conducted a population-based study of 1264 participants aged ≥40 years of age from urban and rural areas of Vientiane Province.
Brad Guo +6 more
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Connexin Mutants Cause Cataracts Through Deposition of Apatite
Cataracts are lens opacities that are among the most common causes of blindness. It is commonly believed that cataracts develop through the accumulation of damage to lens proteins.
Peter J. Minogue +5 more
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The Evolving Role of Ophthalmology Clinics in Screening for Early Alzheimer’s Disease: A Review
Alzheimer’s disease (AD) is the leading cause of dementia, which is a growing public health concern. Although there is no curative treatment for established AD, early recognition and modification of the known risk factors can reduce both severity and the
Paris Dickens, Kanna Ramaesh
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Purpose: To study the prevalence of pseudoexfoliation syndrome (PEX) in diabetics with senile cataracts and compare it to the prevalence in nondiabetic control group.
Sidra Javaid Thakur +2 more
doaj +1 more source

