Results 41 to 50 of about 110,885 (306)

Increased SK3 expression in DM1 lens cells leads to impaired growth through a greater calcium-induced fragility [PDF]

, 2006
Although cataract is a characteristic feature of myotonic dystrophy type 1 (DM1), little is known of the underlying mechanisms. We generated four lens epithelial cell lines derived from DM1 cataracts and two from age-matched, non-DM cataracts. Small-pool
Abe, Alan R. Prescott, Anvret, Behrens, Benders, Collison, Darren G. Monckton, Delamere, Diecke, Duke-Elder, Duncan, Dunne, Fleming, George Duncan, Gomes-Pereira, Gomes-Pereira, Harper, Harris, Hull, James, Jeremy D. Rhodes, Jin, John P. McAbney, Khajavi, Khan, Kimura, Klesert, Lauf, Monckton, O'Cochlain, Pham, Remillard, Renaud, Rhodes, Sanderson, Sarkar, Stocker, Sun, Tapscott, Vergara, Winchester   +40 more
core   +2 more sources

The regulatory role of microRNAs in common eye diseases: A brief review

Frontiers in Genetics, 2023
MicroRNAs (miRNAs) are highly conserved, small non-coding RNA molecules (∼21 nucleotides) that regulate numerous biological processes, including developmental timing, hematopoiesis, organogenesis, apoptosis, cell differentiation, and proliferation either
Javier A. Benavides-Aguilar, Jonathan I. Morales-Rodríguez, Héctor Ambriz-González, Luis M. Ruiz-Manriquez, Luis M. Ruiz-Manriquez, Antara Banerjee, Surajit Pathak, Asim K. Duttaroy, Sujay Paul   +8 more
doaj   +1 more source

Cerulean cataract

Pan African Medical Journal, 2023
We report a case of a 34-year-old woman with a medical history of diabetes type 1 presented to our ophthalmology department due to a progressive diminution of vision in both eyes during the last year. No history of ocular trauma was reported. Her best corrected visual acuity was 20/50 in both eyes.
Meryem Benchekroun Belabbes, Narjisse Taouri   +1 more
openaire   +3 more sources

Muscleblind-like 3 deficit results in a spectrum of age-associated pathologies observed in myotonic dystrophy. [PDF]

, 2016
Myotonic dystrophy type I (DM1) exhibits distinctive disease specific phenotypes and the accelerated onset of a spectrum of age-associated pathologies.
Abdallah, Walid F, Choi, Jongkyu, Comai, Lucio, Dansithong, Warunee, Dixon, Donald M, Jordan, Maria C, Lee, Han Shin, Reddy, Sita, Roos, Kenneth P, Trac, Brandon   +9 more
core   +1 more source

Christmas Tree Cataract - A Cataract that Glitters

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016
A 54-year-old man presented to the Ophthalmology OPD with redness and discharge from his eyes. His vision was 20/20 in both the eyes. There was diffuse conjunctival congestion and mild discharge in both the eyes. On detailed examination, the left eye showed highly refractive, multi-coloured, iridescent crystals in the inferior cortex and nucleus of the
Wakaru Shullai, Lanalyn Thangkhiew, Avonuo Keditsu, Tanie Natung   +3 more
openaire   +4 more sources

Years of sunlight exposure and cataract: a case-control study in a Mediterranean population. [PDF]

, 2007
BACKGROUND: We aimed to investigate the relation between sunlight exposure and risk of cataract. METHODS: We carried out a frequency-matched case-control study of 343 cases and 334 controls attending an ophthalmology outpatient clinic at a primary health-
Chaqués-Alepúz, Vicente, de Stavola, Bianca L, Fletcher, Astrid E, Pastor-Valero, María   +3 more
core   +2 more sources

Photonic Nanomaterials for Wearable Health Solutions

Advanced Materials, EarlyView.
This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park, Jung Woo Leem, Young L. Kim, Chi Hwan Lee   +3 more
wiley   +1 more source

Pediatric cataract

Indian Journal of Ophthalmology, 2017
Pediatric cataract is a leading cause of childhood blindness. Untreated cataracts in children lead to tremendous social, economical, and emotional burden to the child, family, and society. Blindness related to pediatric cataract can be treated with early identification and appropriate management.
Sudarshan Kumar Khokhar, Ganesh Pillay, Chirakshi Dhull, Esha Agarwal, Manish Mahabir, Pulak Aggarwal   +5 more
openaire   +3 more sources

Mechanism of action of VP1-001 in cryAB(R120G)-associated and age-related cataracts [PDF]

, 2019
PurposeWe previously identified an oxysterol, VP1-001 (also known as compound 29), that partially restores the transparency of lenses with cataracts. To understand the mechanism of VP1-001, we tested the ability of its enantiomer, ent-VP1-001, to bind ...
Andley, Usha P., Covey, Douglas F., Dunyak, Bryan M., Gestwicki, Jason E., Hamilton, Paul D., Izrayelit, Yevgeniy, Makley, Leah N., McGlasson-Naumann, Brittney, Molnar, Kathleen S., Qian, Mingxing, Su, Bonnie   +10 more
core   +2 more sources

Effect of plant-based feed ingredients on osmoregulation in the Atlantic salmon lens [PDF]

, 2010
Lenses of adult Atlantic salmon fed with a plant oil and plant protein-based diet (plant diet) were compared to lenses of fish fed a diet based on traditional marine ingredients (marine diet) with respect to biochemical composition and functionality ex ...
Baslow, Bell, Bell, Bell, Bjerkås, Bjerkås, Bjerkås, Bjerkås, Breck, Breck, Breck, Breck, Brodtkorb, Chan, Christiane Tröβe, Delamere, Duston, Hargis, Hawse, Iwata, Jeremy D. Rhodes, Jobling, Jordal, Julie Sanderson, Kantorow, Lu, Menzies, Mizuno, Ng, Nilsen, Olav Breck, Rune Waagbø, Sneddon, Sutherland, Tacon, Toivonen, Torstensen, Torstensen, Torstensen, Tröβe, Tröβe, Turchini, Untergasser, Ursini, Vandesompele, Vemuri, Virtanen, Waagbø, Waagbø, Waagbø, Wall, Yeagle, Zhang   +52 more
core   +1 more source