Results 291 to 300 of about 157,341 (380)

Effect on Dyskinesia of the Early Combination of Amantadine to Levodopa‐Therapy in Parkinson's Disease: A Randomized, Placebo‐Controlled Study (PREMANDYSK)

open access: yesMovement Disorders, EarlyView.
Abstract Objective Investigate the efficacy of immediate‐release (IR) amantadine in reducing the risk of peak‐dose dyskinesia in early Parkinson's disease (PD) as add‐on to levodopa. Background While the use of amantadine to manage dyskinesia in PD is well supported by controlled clinical trials, data on its efficacy in patients without motor ...
Olivier Rascol   +106 more
wiley   +1 more source

Progress on the Application of Polymers of Intrinsic Microporosity for the Adsorption of Organic Contaminants

open access: yesChemistryOpen, EarlyView.
The pictorial illustration of the applications of polymers of intrinsic microporosity extraordinary porous organic polymers with high surface areas, pore radii, pore volumes, high permeability, high diffusivity, high selectivity, and high thermal stability, as suitable filters or purifiers for water contaminated with pharmaceutical and organic dyes ...
Martins O. Omorogie
wiley   +1 more source

The phenol-2-monooxygenase FgPhm1 regulates DON synthesis, pathogenicity and environmental stress response in <i>Fusarium graminearum</i>. [PDF]

open access: yesVirulence
Luo Z   +11 more
europepmc   +1 more source

Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall   +4 more
wiley   +1 more source

NIR‐Responsive Nano‐Integrated Magnesium Phosphate Cement Promotes Bone Regeneration via Osteoblast‐Exosome‐Osteoclast Crosstalk

open access: yesRare Metals, EarlyView.
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang   +8 more
wiley   +1 more source

Responsive liquid metal materials towards unstructured environment

open access: yesResponsive Materials, EarlyView.
Room‐temperature liquid metals integrate conductivity, deformability, and interfacial dynamics, enabling robust performance in unstructured environments. This review highlights key properties, requirements, and applications across in vivo, underwater, natural, space, and radiation settings, with advances in sensing, actuation, thermal regulation, and ...
Bo Yuan   +5 more
wiley   +1 more source

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