The interplay between α-synuclein (α-syn) and catechols plays a central role in Parkinson’s disease. This may be related to the modulating effects of catechols on the various aspects of α-syn fibrillization. Some of these effects may be attributed to the
Toktam Zohoorian-Abootorabi +5 more
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Decoding crosstalk between neurotransmitters and α-synuclein in Parkinson’s disease: pathogenesis and therapeutic implications [PDF]
Parkinson’s disease (PD) is the second most common neurodegenerative disease, characterized by progressive worsening of motor symptoms. The primary pathological hallmark of PD is the degeneration of dopaminergic neurons in the substantia nigra and the ...
Lihua Guan +3 more
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Case Report: A possible novel adult-onset, progressive MAO-A hypofunction [PDF]
We describe the clinical presentation, pathophysiology, and successful treatment of a previously undocumented adult onset, progressive form of monoamine oxidase A hypofunction.
Stefan Berteau, Erik Armitano
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Zirconium-catalyzed one-pot synthesis of benzoxazoles using reaction of catechols, aldehydes and ammonium acetate [PDF]
In this study, an efficient method for the synthesis of benzoxazoles by coupling catechols, aldehydes and ammonium acetate using ZrCl4 as catalyst in ethanol is reported. A wide range of benzoxazoles (59 examples) are smoothly produced in high yields (up
Masoumeh Mohammadi +4 more
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Small phenolic compounds as potential endocrine disruptors interacting with estrogen receptor alpha [PDF]
The human body is regularly exposed to simple catechols and small phenols originating from our diet or as a consequence of exposure to various industrial products.
Raul Alva-Gallegos +3 more
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Exploring the structure and dynamics of soft and hard cuticle of Bombyx mori using solid-state NMR techniques [PDF]
This study conducts a comprehensive analysis and comparison of Bombyx mori cuticles across different developmental stages, ranging from larval to adult, utilizing advanced solid-state NMR techniques.
Lekhan Lodhi +6 more
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Synthesis, electrochemical properties, and antioxidant activity of sterically hindered catechols with 1,3,4-oxadiazole, 1,2,4-triazole, thiazole or pyridine fragments [PDF]
A series of new RS−, RS−CH2− and R2N−CH2-functionalized сatechols with heterocyclic fragments such as 1,3,4-oxadiazole, 1,2,4-triazole, thiazole, or pyridine were synthesized by the reaction of 3,5-di-tert-butyl-o-benzoquinone or 3,5-di-tert-butyl-6 ...
Daria A. Burmistrova +9 more
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Activation of the Nrf2 Cell Defense Pathway by Ancient Foods: Disease Prevention by Important Molecules and Microbes Lost from the Modern Western Diet. [PDF]
The Nrf2 (NFE2L2) cell defense pathway protects against oxidative stress and disorders including cancer and neurodegeneration. Although activated modestly by oxidative stress alone, robust activation of the Nrf2 defense mechanism requires the additional ...
Donald R Senger +3 more
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The Influence of Catechols on the Magnetization of Iron Oxide Nanoparticles
In this study, MNPs were functionalized with pyrocatechol (CAT), pyrogallol (GAL), caffeic acid (CAF), and nitrodopamine (NDA) at pH 8 and pH 11. The functionalization of the MNPs was successful, except in the case of NDA at pH 11.
Stanislav Čampelj +6 more
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Characterizing Electron Flow through Catechol‐Graphene Composite Hydrogels
Electronic materials that allow the controlled flow of electrons in aqueous media are required for emerging applications that require biocompatibility, safety, and/or sustainability.
Eunkyoung Kim +7 more
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