Results 1 to 10 of about 55,807 (381)

Modulation of cytotoxic amyloid fibrillation and mitochondrial damage of α-synuclein by catechols mediated conformational changes

open access: yesScientific Reports, 2023
The interplay between α-synuclein (α-syn) and catechols plays a central role in Parkinson’s disease. This may be related to the modulating effects of catechols on the various aspects of α-syn fibrillization. Some of these effects may be attributed to the
Toktam Zohoorian-Abootorabi   +5 more
doaj   +2 more sources

Adsorption mechanism and valency of catechol-functionalized hyperbranched polyglycerols [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2015
Nature often serves as a model system for developing new adhesives. In aqueous environments, mussel-inspired adhesives are promising candidates. Understanding the mechanism of the extraordinarily strong adhesive bonds of the catechol group will likely ...
Stefanie Krysiak   +5 more
doaj   +8 more sources

Impact of Molecular Architecture and Adsorption Density on Adhesion of Mussel-Inspired Surface Primers with Catechol-Cation Synergy. [PDF]

open access: gold, 2019
Marine mussels secrete proteins rich in residues containing catechols and cationic amines that displace hydration layers and adhere to charged surfaces under water via a cooperative binding effect known as catechol-cation synergy.
Andresen Eguiluz, Roberto C   +7 more
core   +2 more sources

Decoding crosstalk between neurotransmitters and α-synuclein in Parkinson’s disease: pathogenesis and therapeutic implications [PDF]

open access: yesTherapeutic Advances in Neurological Disorders
Parkinson’s disease (PD) is the second most common neurodegenerative disease, characterized by progressive worsening of motor symptoms. The primary pathological hallmark of PD is the degeneration of dopaminergic neurons in the substantia nigra and the ...
Lihua Guan   +3 more
doaj   +2 more sources

Fluorometry of catechol thioethers

open access: goldActa Dermato-Venereologica, 1972
No abstract ...
H Rorsman, AM Rosengren, E. Rosengren
openalex   +4 more sources

Zirconium-catalyzed one-pot synthesis of benzoxazoles using reaction of catechols, aldehydes and ammonium acetate [PDF]

open access: yesScientific Reports
In this study, an efficient method for the synthesis of benzoxazoles by coupling catechols, aldehydes and ammonium acetate using ZrCl4 as catalyst in ethanol is reported. A wide range of benzoxazoles (59 examples) are smoothly produced in high yields (up
Masoumeh Mohammadi   +4 more
doaj   +2 more sources

Small phenolic compounds as potential endocrine disruptors interacting with estrogen receptor alpha [PDF]

open access: yesFrontiers in Endocrinology
The human body is regularly exposed to simple catechols and small phenols originating from our diet or as a consequence of exposure to various industrial products.
Raul Alva-Gallegos   +3 more
doaj   +2 more sources

Exploring the structure and dynamics of soft and hard cuticle of Bombyx mori using solid-state NMR techniques [PDF]

open access: yesScientific Reports
This study conducts a comprehensive analysis and comparison of Bombyx mori cuticles across different developmental stages, ranging from larval to adult, utilizing advanced solid-state NMR techniques.
Lekhan Lodhi   +6 more
doaj   +2 more sources

Synthesis, electrochemical properties, and antioxidant activity of sterically hindered catechols with 1,3,4-oxadiazole, 1,2,4-triazole, thiazole or pyridine fragments [PDF]

open access: yesBeilstein Journal of Organic Chemistry
A series of new RS−, RS−CH2− and R2N−CH2-functionalized сatechols with heterocyclic fragments such as 1,3,4-oxadiazole, 1,2,4-triazole, thiazole, or pyridine were synthesized by the reaction of 3,5-di-tert-butyl-o-benzoquinone or 3,5-di-tert-butyl-6 ...
Daria A. Burmistrova   +9 more
doaj   +2 more sources

Activation of the Nrf2 Cell Defense Pathway by Ancient Foods: Disease Prevention by Important Molecules and Microbes Lost from the Modern Western Diet. [PDF]

open access: yesPLoS ONE, 2016
The Nrf2 (NFE2L2) cell defense pathway protects against oxidative stress and disorders including cancer and neurodegeneration. Although activated modestly by oxidative stress alone, robust activation of the Nrf2 defense mechanism requires the additional ...
Donald R Senger   +3 more
doaj   +1 more source

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