Results 11 to 20 of about 6,092 (260)

Modulation of cytotoxic amyloid fibrillation and mitochondrial damage of α-synuclein by catechols mediated conformational changes

open access: yesScientific Reports, 2023
The interplay between α-synuclein (α-syn) and catechols plays a central role in Parkinson’s disease. This may be related to the modulating effects of catechols on the various aspects of α-syn fibrillization. Some of these effects may be attributed to the
Toktam Zohoorian-Abootorabi   +5 more
doaj   +1 more source

Decoding crosstalk between neurotransmitters and α-synuclein in Parkinson's disease: pathogenesis and therapeutic implications. [PDF]

open access: yesTher Adv Neurol Disord
Parkinson’s disease (PD) is the second most common neurodegenerative disease, characterized by progressive worsening of motor symptoms. The primary pathological hallmark of PD is the degeneration of dopaminergic neurons in the substantia nigra and the ...
Guan L, Lin L, Ma C, Qiu L.
europepmc   +2 more sources

Activation of the Nrf2 Cell Defense Pathway by Ancient Foods: Disease Prevention by Important Molecules and Microbes Lost from the Modern Western Diet. [PDF]

open access: yesPLoS ONE, 2016
The Nrf2 (NFE2L2) cell defense pathway protects against oxidative stress and disorders including cancer and neurodegeneration. Although activated modestly by oxidative stress alone, robust activation of the Nrf2 defense mechanism requires the additional ...
Donald R Senger   +3 more
doaj   +1 more source

Characterizing Electron Flow through Catechol‐Graphene Composite Hydrogels

open access: yesAdvanced Materials Interfaces, 2022
Electronic materials that allow the controlled flow of electrons in aqueous media are required for emerging applications that require biocompatibility, safety, and/or sustainability.
Eunkyoung Kim   +7 more
doaj   +1 more source

From Surfactants to Viscoelastic Capsules

open access: yesAdvanced Materials Interfaces, 2023
Micrometer sized capsules are often used as single entities for the encapsulation and release of active ingredients, for example in food, cosmetics, and drug delivery.
Gaia De Angelis   +3 more
doaj   +1 more source

Advances in 4-Hydroxyphenylacetate-3-hydroxylase Monooxygenase

open access: yesMolecules, 2023
Catechols have important applications in the pharmaceutical, food, cosmetic, and functional material industries. 4-hydroxyphenylacetate-3-hydroxylase (4HPA3H), a two-component enzyme system comprising HpaB (monooxygenase) and HpaC (FAD oxidoreductase ...
Kai Yang   +7 more
doaj   +1 more source

Case Report: A possible novel adult-onset, progressive MAO-A hypofunction. [PDF]

open access: yesFront Neurosci
We describe the clinical presentation, pathophysiology, and successful treatment of a previously undocumented adult onset, progressive form of monoamine oxidase A hypofunction.
Berteau S, Armitano E.
europepmc   +2 more sources

Catechol-Based Hydrogel for Chemical Information Processing

open access: yesBiomimetics, 2017
Catechols offer diverse properties and are used in biology to perform various functions that range from adhesion (e.g., mussel proteins) to neurotransmission (e.g., dopamine), and mimicking the capabilities of biological catechols have yielded important ...
Eunkyoung Kim   +4 more
doaj   +1 more source

1st Symposium on Polydopamine and NanoTech Poland 2018: Conference Report

open access: yesBiomimetics, 2018
The NanoTech Poland is an annual international conference with a strong scientific agenda focused on nanotechnology in energy, environment, and biomedicine.
Radosław Mrówczyński   +3 more
doaj   +1 more source

A process optimization for bio-catalytic production of substituted catechols (3-nitrocatechol and 3-methylcatechol

open access: yesBMC Biotechnology, 2010
Background Substituted catechols are important precursors for large-scale synthesis of pharmaceuticals and other industrial products. Most of the reported chemical synthesis methods are expensive and insufficient at industrial level.
Tiwary Bhupendra N   +3 more
doaj   +1 more source

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