Results 21 to 30 of about 7,970 (248)

The Role of Human Aldo-Keto Reductases (AKRs) in the Metabolic Activation and Detoxication of Polycyclic Aromatic Hydrocarbons: Interconversion of PAH-catechols and PAH o-Quinones

open access: yesFrontiers in Pharmacology, 2012
Polycyclic aromatic hydrocarbons (PAH) are ubiquitous environmental pollutants. They are procarcinogens requiring metabolic activation to elicit their deleterious effects.
Li eZhang   +3 more
doaj   +1 more source

Controlling mechanical properties of bio-inspired hydrogels by modulating nano-scale, inter-polymeric junctions

open access: yesBeilstein Journal of Nanotechnology, 2014
Quinone tanning is a well-characterized biochemical process found in invertebrates, which produce diverse materials from extremely hard tissues to soft water-resistant adhesives.
Seonki Hong, Hyukjin Lee, Haeshin Lee
doaj   +1 more source

A redox-neutral catechol synthesis

open access: yesNature Communications, 2017
Catechols are common structural motifs in bioactive molecules and synthetic building blocks. Here the authors report a method to convert phenol derivatives into catechols via an iridium-catalysed redox-neutral C–H hydroxylation, giving diversely ...
Qian Wu   +9 more
doaj   +1 more source

In vitro evaluation of the effect of C-4 substitution on methylation of 7,8-dihydroxycoumarin: metabolic profile and catalytic kinetics [PDF]

open access: yesRoyal Society Open Science, 2018
Daphnetin (7,8-dihydroxycoumarin (7,8-DHC)) and its C-4 derivatives have multiple pharmacological activities, but the poor metabolic stability of these catechols has severely restricted their application in the clinic.
Yang-Liu Xia   +5 more
doaj   +1 more source

Pro- and Anti-oxidant Properties of Redox-Active Catechol-Chitosan Films

open access: yesFrontiers in Chemistry, 2019
Catechols are abundant in nature and are believed to perform diverse biological functions that include photoprotection (e.g., melanins), molecular signaling (e.g., catecholamine neurotransmitters), and mechanical adhesion (e.g., mussel glue).
Eunkyoung Kim   +7 more
doaj   +1 more source

Mussel‐Inspired Polyglycerol Coatings for Surface Modification with Tunable Architecture

open access: yesAdvanced Materials Interfaces, 2023
Mussel‐inspired coatings, known for their outstanding substrate‐independent adhesive capabilities, have numerous potential applications in materials science and biomedical fields.
Peng Tang   +5 more
doaj   +1 more source

Electrooxidation of Catechols in the Presence of Sulfite: Presentation of a Facile and Green Method for Aromatic Sulfonation

open access: yesInternational Journal of Electrochemical Science, 2007
Electrochemical oxidation of catechols (1a-e) has been studied in the presence of sulfite ion (3) as nucleophile in aqueous solution, using cyclic voltammetry and controlled-potential coulometry. The results indicate the participation of catechols (1a-e)
D. Nematollahi, E. Tammari, H. Karbasi
doaj   +1 more source

Digital Simulation of the Cyclic Voltammetric Study of the Catechols Electrooxidation in the Presence of Thiourea

open access: yesInternational Journal of Electrochemical Science, 2011
The present work explains the electrochemical behavior of catechols in the presence of thiourea as a nucleophile in aqueous solution, by means of cyclic voltammetry and controlled-potential coulometry.
Bahram Dowlati   +2 more
doaj   +1 more source

Nucleophilic Deoxyfluorination of Catechols

open access: yes, 2016
Nucleophilic deoxyfluorinaiton of one of the two hydroxyl groups of catechols has been developed via the Umpolung concept. This method was successively applied to naturally occurring catechols, such as catechins and dopamine, to produce novel fluorinated
Shuji Akai (1923553)   +2 more
core   +1 more source

Enzymatic Allylation of Catechols

open access: yes, 2015
Enzymatic allylation of catechols was realized via catechol O-methyltransferase (COMT) using an allylated S-adenosyl-L-methionine (allyl-SAM) analog, with relatively good chemo- and regioselectivities.
Liu, Yuxue   +5 more
core   +1 more source

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