Results 91 to 100 of about 1,780,327 (266)
Speaking Stata: Graphing categorical and compositional data [PDF]
A variety of graphs have been devised for categorical and compositional data, ranging from widely familiar to more unusual displays. Both official Stata commands and user-written programs are available.
Nicholas J. Cox
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Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Analyzing Biomedical Datasets with Symbolic Tree Adaptive Resonance Theory
InformationBiomedical datasets distill many mechanisms of human diseases, linking diseases to genes and phenotypes (signs and symptoms of disease), genetic mutations to altered protein structures, and altered proteins to changes in molecular functions and ...
Sasha Petrenko +7 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Application of Genetic Algorithm Based Intuitionistic Fuzzy k-Mode for Clustering Categorical Data
Cybernetics and Information Technologies, 2017 In present times a great number of clustering algorithms are available which group objects having similar features. But most of the datasets have data values that are categorical, which makes it difficult to implement these algorithms.
Goyal Akarsh +2 more
doaj +1 more source
Clustering of categorical variables around latent variables [PDF]
In the framework of clustering, the usual aim is to cluster observations and not variables. However the issue of variable clustering clearly appears for dimension reduction, selection of variables or in some case studies (sensory analysis, biochemistry ...
Jérome SARACCO (GREThA UMR CNRS 5113) +2 more
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Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Comparison of methods in the analysis of dependent ordered catagorical data [PDF]
Rating scales for outcome variables produce categorical data which are often ordered and measurements from rating scales are not standardized. The purpose of this study is to apply commonly used and novel methods for paired ordered categorical data to ...
Högberg, Hans, Svensson, Elisabeth
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