Results 111 to 120 of about 1,546,902 (293)

Stacks of group representations [PDF]

, 2013
We start with a small paradigm shift about group representations, namely the observation that restriction to a subgroup can be understood as an extension-of-scalars.
Balmer, Paul
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Non-degeneracy of cohomological traces for general Landau-Ginzburg models

, 2018
We prove non-degeneracy of the cohomological bulk and boundary traces for general open-closed Landau-Ginzburg models associated to a pair $(X,W)$, where $X$ is a non-compact complex manifold with trivial canonical line bundle and $W$ is a complex-valued ...
Doryn, Dmitry, Lazaroiu, Calin Iuliu
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Dinamika dan Daya Saing Sektor Pertanian di Kabupaten Padang Pariaman, Sumatera Barat

Jurnal Ilmu Pertanian Indonesia
Regional economic development is closely related to the role of the agricultural sector. In addition to food production, agriculture also contributes to the absorption of labor.
Zori Mahendra, Widya Fitriana, Yuerlita Yuerlita   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Beyond promotion-based store switching: Antecedents and patterns of systematic multiple-store shopping (revised version). [PDF]

In this paper, we demonstrate both theoretically and empirically that single-purpose multiple store shopping is not only driven by opportunistic, promotion-based motivations, but may also result from a longer term planning process based on stable store ...
Campo, Katia, Gijsbrechts, Els, Nisol, Patricia   +2 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

PSYCHOLOGICAL ASSESSMENT OF EXTREMIST TEXTS: THEORETICAL ASPECTS

Теория и практика судебной экспертизы, 2014
The paper argues for a need to shift the emphasis from text to person when assessing suspected extremist materials. It examines theoretical rationale behind the scope, objects and objectives of psychological assessment in this category of integrated ...
D. Berdnikov
doaj  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source