Results 191 to 200 of about 220,813 (310)

Correlation between CK1α and β-catenin Ser45-phosphorylation in patients with esophageal squamous cell carcinoma.

, 2019
Xinning Pan, Lili Ma, Jinsheng Wang
openalex   +1 more source

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

Impaired nitrogenous waste clearance promotes hepatocellular carcinoma. [PDF]

Sci Adv
Han X, Shen J, Yan J, Tacke R, Dai W, Mao Q, Queen Daguplo H, Liu S, Islam A, Liu T, Koch MC, Lin RZ, Li H, Anthony T, Xie P, Zhang L, Gao S, Simon MC, Chen X, Yang J, Su X, Zong WX.   +21 more
europepmc   +1 more source

Tumor heterogeneity in small hepatocellular carcinoma: Analysis of tumor cell proliferation, expression and mutation of p53 AND ?-catenin [PDF]

, 2001
Feng-Qi An, Masanori Matsuda, Hideki Fujii, Rui‐Feng Tang, Hideki Amemiya, Yuemeng Dai, Yoshirô Matsumoto   +6 more
openalex   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

Circadian Clock Dysfunction Exacerbate Autistic-Like Behaviour and Wnt/β-Catenin Signalling Dysregulation in ASD Mice and Treatment of Melatonin. [PDF]

J Cell Mol Med
Zhang Y, Chen Y, Li W, Tang L, Wang G, Li J, Feng X.   +6 more
europepmc   +1 more source

Inhibition of β‑catenin protein expression by triptolide affects self-renewal of liver cancer stem cells

, 2015
Jianbo Zhou, Gang Peng, Yu-Cheng Jia, ­Jun Li­, Jia Wang, Shu Nie, Qiuying Zhang   +6 more
openalex   +2 more sources

PCDH20 functions as a tumour‐suppressor gene through antagonizing the Wnt/β‐catenin signalling pathway in hepatocellular carcinoma [PDF]

, 2014
Jia Lv, Pengfei Zhu, Ziwei Yang, M. Li, Xiaojuan Zhang, Jin Cheng, X. Chen, Fengmin Lu   +7 more
openalex   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

Lymphoid enhancer-binding factor 1 (LEF1) immunostaining as a surrogate for β-catenin (<i>CTNNB1</i>) mutations. [PDF]

J Clin Pathol
Hewer E, Fischer PD, Vassella E, Knabben L, Imboden S, Mueller MD, Rau TT, Dettmer MS.   +7 more
europepmc   +1 more source