Results 231 to 240 of about 220,813 (310)

Albiflorin enhances the antitumor effects of propofol in hepatocellular carcinoma cells by inhibiting the Wnt/β-catenin signaling activation. [PDF]

Transl Cancer Res
Ji T, Ye L, Xu C, Ma C, Yin G.
europepmc   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Bone mesenchymal stem cells-derived exosomal miR-509-5p promotes osteogenic differentiation by targeting SFRP1 and activating the Wnt/β-catenin pathway. [PDF]

Sci Rep
Liu L, Sun W, Li B, Wang J.
europepmc   +1 more source

Extramedullary Disease—Achilles Heel in Myeloma?

American Journal of Hematology, EarlyView.
ABSTRACT Despite advances in therapy, extramedullary disease (EMD) remains an aggressive form of multiple myeloma associated with poor outcomes. Patients with true EMD, in which plasmacytomas have become completely independent of bone, have a particularly poor prognosis. The pathogenesis of EMD is driven by complex mechanisms involving loss of adhesion
Shaji Kumar, Joshua Richter, Saad Z. Usmani, Yael C. Cohen, Jing Christine Ye, María‐Victoria Mateos, Vania Hungria, Elena Zamagni   +7 more
wiley   +1 more source

FoxO1 Responses to Chronic Oxidative Stress to Participate in Age-Related Osteoporosis by Depriving β-Catenin From TCF7. [PDF]

Aging Cell
Su P, Ma X, Yin C, Shi R, Chen S, Yang L, Qu M, Jia X, Yu Q, Li H, Qian A, Tian Y.   +11 more
europepmc   +1 more source

Promotion Effect of Apo-9′-fucoxanthinone from <i>Sargassum muticum</i> on Hair Growth <i>via</i> the Activation of Wnt/β-Catenin and VEGF-R2

, 2016
Jung-Il Kang, Eun-Sook Yoo, Jin Won Hyun, Young‐Sang Koh, Nam Ho Lee, Mi-Hee Ko, Chang-Sik Ko, Hee‐Kyoung Kang   +7 more
openalex   +1 more source

CBX4 Drives Gastric Cancer Progression by Activating <b>β</b>-Catenin Signaling. [PDF]

Oncol Res
Jia W, Zhang T, Zhang Z, Wu L, Fu X, Wang Z, Yin N.   +6 more
europepmc   +1 more source

UBE3A stabilization of β-catenin preserves synaptic proteins essential for motor and cognitive functions in Angelman Syndrome. [PDF]

Mol Autism
Yang X, Huang YA, Marshall J.
europepmc   +1 more source

Evaluation of IHH, PTCH1, and SMO protein immunohistochemistry in the human mandibular condyle at fetal stages from 30 to 80 mm greatest length

The Anatomical Record, EarlyView.
Abstract This study evaluated the morphogenesis of the temporomandibular joint (TMJ) in human fetuses during the third month of gestation through the analysis of immunohistochemistry for the proteins Indian Hedgehog (IHH), Patched‐1 (PTCH1), and Smoothened (SMO).
Filipe Santos da Silva, Carolina de Oliveira Gigek, Andreia Fabiana Do Vale Franco, Amanda Alves Ribeiro Massoni, José Ramon Mérida‐Velasco, Luís Otávio Carvalho de Moraes   +5 more
wiley   +1 more source

Overexpression of nuclear β-catenin in rectal adenocarcinoma is associated with radioresistance

, 2013
Zhen Li
openalex   +2 more sources