Results 111 to 120 of about 24,735 (220)

Vitamin D deficiency in human and murine sepsis [PDF]

, 2017
Objectives: Vitamin D deficiency has been implicated as a pathogenic factor in sepsis and ICU mortality but causality of these associations has not been demonstrated.
Amrein, Braun, Braun, Cannell, Danai, Dancer, de Haan, Dellinger, Gombart, Greenwood, Hyppönen, Jeng, Kovach, Lax, Leaf, Leaf, Marcinowska-Suchowierska, Moromizato, Møller, Nair, Nathani, Owens, Parekh, Parekh, Patel, Quraishi, Remmelts, Sherman, Shoben, Thickett, Upala, van Schoor   +31 more
core   +3 more sources

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis

Journal of Gastroenterology and Hepatology, Volume 41, Issue 5, Page 1446-1458, May 2026.
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen, Caihan Duan, Keyi Zhang, Jun Liu, Chaoqun Han   +4 more
wiley   +1 more source

Flagellin induces β-defensin 2 in human colonic ex vivo infection with enterohemorrhagic Escherichia coli [PDF]

, 2016
Enterohemorrhagic E. coli (EHEC) is an important foodborne pathogen in the developed world and can cause life-threatening disease particularly in children.
Chan, Simon, Cook, Vivienne, Ellis, Samuel, Gelson, William, Lewis, Steven, Prior, Alison, Schuller, Stephanie   +6 more
core   +1 more source

Amniotic fluid cathelicidin in PPROM pregnancies: from proteomic discovery to assessing its potential in inflammatory complications diagnosis.

PLoS ONE, 2012
BackgroundPreterm prelabor rupture of membranes (PPROM) complicated by microbial invasion of the amniotic cavity (MIAC) leading to histological chorioamnionitis (HCA) significantly impacts perinatal morbidity.
Vojtech Tambor, Marian Kacerovsky, Marian Kacerovsky, Ctirad Andrys, Ivana Musilova, Helena Hornychova, Lenka Pliskova, Marek Link, Jiri Stulik, Juraj Lenco   +9 more
doaj   +1 more source

Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal. [PDF]

, 2019
Proteins involved in lipoprotein metabolism can modulate cardiovascular health. While often measured to assess adult metabolic diseases, little is known about the proteomes of lipoproteins and their relation to metabolic dysregulation and underlying ...
Christian, Parul, Cole, Robert N, Eroglu, Abdulkerim, Groopman, John, Lee, Sun Eun, Schulze, Kerry, Stewart, Christine P, West, Keith P, Wu, Lee S-F, Yager, James D   +9 more
core  

[Cathelicidins - endogenous antimicrobial peptides].

Postepy biochemii, 2015
Within the last decade, several antimicrobial peptides (AMPs) have been discovered. Cathelicidins are one family of AMPs characterized by a conserved cathelin domain and a variable C-terminal cationic antimicrobial domain. These peptides are produced by different cells, including leukocytes, epithelial cells and keratinocytes.
Karolina, Wódz, Ewa, Brzezińiska-Błaszczyk   +1 more
openaire   +1 more source

Vitamin D and cathelicidin assessment in infection-induced asthma in Egyptian children

Bulletin of the National Research Centre, 2019
Introduction Vitamin D deficiency was hypothesized to increase the risk of respiratory infections and asthma exacerbation through a reduced production of cathelicidin, a multifunctional anti-microbial peptide essential for normal immune responses to ...
Hanan M. Hamed, Ayat A. Motawie, Amany M. Abd Al-Aziz, Amal A. Abou El-Ezz, Mona A. M. Awad, Rasha Nazih Yousef   +5 more
doaj   +1 more source

Antifibrogenic Effects of the Antimicrobial Peptide Cathelicidin in Murine Colitis-Associated FibrosisSummary

Cellular and Molecular Gastroenterology and Hepatology, 2015
Background & Aims: Cathelicidin (LL-37 in human and mCRAMP in mice) represents a family of endogenous antimicrobial peptides with anti-inflammatory effects.
Jun Hwan Yoo, Samantha Ho, Deanna Hoang-Yen Tran, Michelle Cheng, Kyriaki Bakirtzi, Yuzu Kubota, Ryan Ichikawa, Bowei Su, Diana Hoang-Ngoc Tran, Tressia C. Hing, Irene Chang, David Q. Shih, Richard E. Issacson, Richard L. Gallo, Claudio Fiocchi, Charalabos Pothoulakis, Hon Wai Koon   +16 more
doaj   +1 more source

Vitamin D3 loaded polycaprolactone nanoparticles enhance the expression of the antimicrobial peptide cathelicidin in macrophages

Artificial Cells, Nanomedicine, and Biotechnology
Tuberculosis (TB), primarily caused by Mycobacterium tuberculosis, remains a global health burden. Current antibiotic treatments are limited by adverse effects, poor adherence, and drug resistance, necessitating new therapeutic approaches. Recent studies
Prince N. Dlozi, Rami Ahmed, Star Khoza, Admire Dube   +3 more
doaj   +1 more source

LL37, a human antimicrobial peptide with immunomodulatory properties [PDF]

, 2011
Cationic antimicrobial peptides (AMPs) represent the first line of defense against many invading pathogens. These small amphipathic peptides are part of the innate immune system and have a broad-spectrum activity against bacteria, fungi and viruses. In
Domingues, Lucília, Gama, F. M., Ramos, Reinaldo Rodrigues   +2 more
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