Results 111 to 120 of about 17,552 (216)

Applications of Cathelicidin

, 2013
A recombinant form of human antimicrobial polypeptide, LL-37 Cathelicidin, was designed and expressed in human cells with the goal for the peptide to incorporate into cell-derived extracellular matrix.
Miller, Chelsea Ross, Gasper, Raymond James   +1 more
core   +4 more sources

Cathelicidin regulates goblet cell mucus secretion and mucus-associated proteins in Citrobacter rodentium-induced colitis

Gut Microbes
Colonic goblet cells play a crucial role in mucosal defense by secreting Muc2 mucin and other proteins that entrap and expel enteropathogens. However, the role of innate effectors in the gut like cathelicidin peptides in regulating the mucus barrier ...
Niloofar Mirzadzare, Graham A. D. Blyth, Rita Hannawayya, Karina M. Cirone, Geeta Kilari, Priyoshi Lahiri, Yi Lin Tan, Aydin Ivan Herik, Yongpeng Fu, Hayley Gorman, Björn Petri, Kris Chadee, Eduardo R. Cobo   +12 more
doaj   +1 more source

Scanning electron microscopy analysis of cathelicidin-RC1-treated bacteria.

, 2014
(A) Control S. aureus ATCC25923; (B) Cathelicidin-RC1-treated S. aureus ATCC25923; (C) Control E. coli ATCC25922; (D) Cathelicidin-RC1-treated E. coli ATCC25922.
Guiying Ling (543925), Zeping Xie (543927), Shumin Zhang (187205), Lin Wei (70005), Haining Yu (227578), Jiuxiang Gao (543926), Yipeng Wang (9800)   +6 more
core   +1 more source

Expression of the antimicrobial peptide cathelicidin in myeloid cells is required for lung tumor growth.

, 2014
Antimicrobial peptides, such as the cathelicidin LL-37/hCAP-18 and its mouse homolog cathelicidin-related antimicrobial peptide (CRAMP), are important effectors of the innate immune system with direct anti-bacterial activity.
Li, D;Beisswenger, C;Herr, C;Schmid, R M;Gallo, R L;Han, G;Zakharkina, T;Bals, R
core   +1 more source

Sensitivity of Chlamydia spp. to cathelicidin peptides

, 2007
Several studies have reported an antimicrobial activity of cathelicidin peptides against bacteria, fungi, protozoa. Since chlamydia sensitivity to cathelicidin peptides has not been systematically tested, we comparatively analysed the activity of six ...
Gennaro R., Shurdhi A., Accardo S., Magnino S., Pignanelli S., DONATI, MANUELA, DI FRANCESCO, ANTONIETTA, CEVENINI, ROBERTO, Benincasa M.   +8 more
core   +1 more source

Two cathelicidin genes are present in both rainbow trout (Oncorhynchus mykiss) and Atlantic salmon (Salmo salar)

, 2006
Further to the previous finding of the rainbow trout rtCATH_1 gene, this paper describes three more cathelicidin genes found in salmonids: two in Atlantic salmon, named asCATH_1 and asCATH_2, and one in rainbow trout, named rtCATH_2.
Zou, J, Zhang, YA, Nie, P, Secombes, CJ, Chang, CI, Secombes, CJ, Univ Aberdeen, Scottish Fish Immunol Res Ctr, Sch Biol Sci, Zool Bldg,Tillydrone Ave, Aberdeen AB24 2TZ, Scotland   +5 more
core   +1 more source

Immunohistochemistry using antibodies to the cathelicidin LL37/hCAP18 in the tammar wallaby, Macropus eugenii

, 2008
Antibodies to the human cathelicidin, hCAP18 have been used to examine epithelial tissues of adult and pouch young marsupials. Immunoreactivity was observed in skin, gastrointestinal tract, lung and mammary node of adults as well as skin ...
Simonian, Nicholas A., Jacques, Nicholas A., Deane, Elizabeth M. (R13183), Old, Julie M. (R11445), Mary R. Simonian, Rebecca L. Carman, Elizabeth M. Deane, Julie M. Old, Carman, Rebecca L., Nicholas A. Jacques   +9 more
core   +1 more source

Antiviral potential of cathelicidins

, 2014
The global burden of morbidity and mortality arising from viral infections is high; however, the development of effective therapeutics has been slow. As our understanding of innate immunity has expanded over recent years, knowledge of natural host defenses against viral infections has started to offer potential for novel therapeutic strategies. An area
Barlow, Peter G, Gwyer Findlay, Emily, Currie, Silke M, Davidson, Donald J   +3 more
openaire   +1 more source

Recent advances in the therapeutic potential of cathelicidins

Frontiers in Microbiology
The alarming increase in antimicrobial resistance in the last decades has prompted the search for alternatives to control infectious diseases. Antimicrobial peptides (AMPs) represent a heterogeneous class of molecules with ample antibacterial, antiviral, and antifungal effects.
Maria Eduarda Souza Guerra, Brenda Vieira, Ana Paula Carvalho Thiers Calazans, Giulia Vicente Destro, Karina Melo, Emilly Rodrigues, Natalha Tedeschi Waz, Raquel Girardello, Michelle Darrieux, Thiago Rojas Converso   +9 more
openaire   +3 more sources

Neutrophil derived cathelicidin in arterial inflammation

, 2013
Neutrophils are the first immune cells recruited into tissues during inflammatory processes. They orchestrate the progression of inflammation through the release of preformed granule proteins such as cathelicidin, azurocidin and alpha-defensin.
Wantha, Sarawuth
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