Results 101 to 110 of about 24,735 (220)

Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro [PDF]

, 2018
Background: There is a need to prevent and treat infection in newborns. One approach is administration of antimicrobial proteins and peptides (APPs) such as LL-37, a membrane-active cathelicidin antimicrobial peptide, and mannose-binding lectin (MBL), a ...
Borriello, Francesco, Jeffers, Carleen, Joshi, Sweta, Levy, Ofer, Li, Ning, Ozonoff, Al, Pettengill, Matthew, Scheid, Annette   +7 more
core   +1 more source

The potential for immunoglobulins and host defense peptides (HDPs) to reduce the use of antibiotics in animal production [PDF]

, 2018
Innate defense mechanisms are aimed at quickly containing and removing infectious microorganisms and involve local stromal and immune cell activation, neutrophil recruitment and activation and the induction of host defense peptides (defensins and ...
A Al-Mamun, A Calmette, A Dijk van, A Dijk van, A Gronberg, A Kalita, A Lihme, A Nijnik, AH Achtman, AL Hilchie, Albert van Dijk, AM Does van der, AS Ferreira, B Rivas-Santiago, BA Blok, BS Graham, C Subbalakshmi, CD Fjell, Chris J. Hedegaard, CJ Hedegaard, CJ Hedegaard, CJ Hedegaard, CSF Bah, D Carlander, D Torrallardona, D Yang, D Yang, DA O’Neil, DA O’Neil, DC Speksnijder, DJ Davidson, DM Bowdish, DM Weaver, E Miraglia, E Tourneur, F Nimmerjahn, G Marano, G Vidarsson, H Liu, H Sherman, Henk P. Haagsman, I Nagaoka, J Kindrachuk, J Kleinnijenhuis, J Kovacs-Nolan, J Kovacs-Nolan, J Kovacs-Nolan, J Rohrl, J Schauber, JB Schaal, JD Heilborn, JH Es van, JL Pierce, K Chakraborty, K Chakraborty, K Moor, K Putsep, L Bandholtz, L Kannan, L Steinstraesser, L Zhang, LT Sunkara, M Akdis, M Cappelletti, M Coorens, M Coorens, M Ohno, M Ren, M Schlee, M Schlee, M Schwab, MA Hamon, MA Keller, MD Kraaij, MG Netea, MJ Alam, MM Rahman, N Mookherjee, N Mookherjee, NH Salzman, NY Yount, OE Sorensen, P Fehlbaum, P Presicce, P Sarker, P Tewary, Peter M. H. Heegaard, R Fisher, R Nocerino, R Ramos, R Raqib, RA Dorschner, RE Hancock, RE Hancock, RE Hancock, RI Lehrer, RJ Arts, RL Gallo, RL Hassfurther, RP Darveau, RS Rekha, S Caro Di, S Godden, S Saeed, SH Kim, T Cuperus, T Cuperus, TA Pham, TJ Newby, U Gerstel, V Petrov, V Virdi, VA Schneider, VK Lishko, W Jiang, WL Hurley, X Qiu, X Zeng, Y Goto   +118 more
core   +2 more sources

A Botanical Mixture of Boswellia serrata, Commiphora myrrha, Propolis and Scutellaria baicalensis Reduces Expression of Inflammatory Chemokines in Canine Keratinocytes In Vitro

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
YSK‐AB, a botanical mixture, reduced nitric oxide production in RAW 264.7 cells and chemokine expression in canine keratinocytes, suggesting its potential as a natural therapeutic agent for inflammatory skin diseases in dogs. ABSTRACT Background Botanical ingredients can function as adjunctive therapies for managing inflammatory skin diseases ...
Danbee Ha, Kyungsook Jung, Hyungyeong Choi, Ji‐Seon Yoon   +3 more
wiley   +1 more source

Nasal cathelicidin is expressed in early life and is increased during mild, but not severe respiratory syncytial virus infection

Scientific Reports
Respiratory syncytial virus is the major cause of acute lower respiratory tract infections in young children, causing extensive mortality and morbidity globally, with limited therapeutic or preventative options.
Sofia Sintoris, Justyna M. Binkowska, Jonathan L. Gillan, Roy P. Zuurbier, Jonathan Twynam-Perkins, Maartje Kristensen, Lauren Melrose, Paula Lusaretta Parga, Alicia Ruiz Rodriguez, Mei Ling Chu, Sara R. van Boeckel, Joanne G. Wildenbeest, Dawn M. E. Bowdish, Andrew J. Currie, Ryan S. Thwaites, Jurgen Schwarze, Marlies A. van Houten, James P. Boardman, Steve Cunningham, Debby Bogaert, Donald J. Davidson   +20 more
doaj   +1 more source

Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics. [PDF]

, 2019
Endovascular infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a major health care concern, especially infective endocarditis (IE).
Abdelhady, Wessam, Bayer, Arnold S, Chambers, Henry F, Ersoy, Selvi C, Li, Liang, Xiong, Yan Q   +5 more
core  

T Cell Immunosenescence in Inflammatory Skin Diseases: Pathogenesis and Therapeutic Targets

Aging Cell, Volume 25, Issue 5, May 2026.
Immunosenescent T cells promote inflammatory skin diseases such as psoriasis, atopic dermatitis, rosacea, and seborrheic dermatitis via hyperactive signaling networks and SASP secretion. Consequently, intercepting downstream SASP, inhibiting internal pathways, or utilizing senolytics represents promising therapeutic interventions.
Conghui Liu, Ming Yang, Fugang Xiao, Jinrong Zeng   +3 more
wiley   +1 more source

Avian host defense cathelicidins: structure, expression, biological functions, and potential therapeutic applications

Poultry Science, 2020
Host defense peptides (HDP) are multifunctional effectors of the innate immune system, which has antimicrobial and pleiotropic immunomodulatory functions.
Yingjie Wang, Min Wang, Anshan Shan, Xingjun Feng   +3 more
doaj   +1 more source

Linezolid and Rifampicin Combination to Combat cfr-Positive Multidrug-Resistant MRSA in Murine Models of Bacteremia and Skin and Skin Structure Infection. [PDF]

, 2019
Linezolid resistance mediated by the cfr gene in MRSA represents a global concern. We investigated relevant phenotype differences between cfr-positive and -negative MRSA that contribute to pathogenesis, and the efficacy of linezolid-based combination ...
Li, Liang, Liao, Xiao-Ping, Liu, Ya-Hong, Sun, Jian, Tao, Meng-Ting, Xiong, Yan Q, Zhou, Yu-Feng   +6 more
core  

Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract

American Journal of Reproductive Immunology, Volume 95, Issue 5, May 2026.
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik, Shreya Joshi, Aisha Nazli, Charu Kaushic   +3 more
wiley   +1 more source

Eubiosis and dysbiosis: the two sides of the microbiota [PDF]

, 2016
The microbial ecosystem of the gastrointestinal tract is characterized by a great number of microbial species living in balance by adopting mutualistic strategies. The eubiosis/dysbiosis condition of the gut microbiota strongly influences our healthy and
Cacciotti, Fatima, Cicerone, Clelia, Corazziari, Enrico Stefano, Gagliardi, Antonella, Iebba, Valerio, Mancini, Carlo, Pantanella, Fabrizio, Santangelo, Floriana, Schippa, Serena, Totino, Valentina, Trancassini, Maria   +10 more
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