Results 81 to 90 of about 17,552 (216)
Frontiers in Immunology, 2020 Cationic host defense peptides (CHDP) are immunomodulatory molecules that control infections and contribute to immune homeostasis. CHDP such as cathelicidin and calprotectin expression is altered in the arthritic synovium, and in the lungs of asthma and ...
Mahadevappa Hemshekhar +10 more
doaj +1 more source
Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
The role of cathelicidins in neutrophil biology
Journal of Leukocyte BiologyAbstract Despite their relatively short lifespan, neutrophils are tasked with counteracting pathogens through various functions, including phagocytosis, production of reactive oxygen species, neutrophil extracellular traps (NETs), and host defense peptides.
Grace Yoon +4 more
openaire +2 more sources
Host Cathelicidin Exacerbates Group B
mSphere, 2020 Group B Streptococcus (GBS) causes frequent urinary tract infection (UTI) in susceptible populations, including individuals with type 2 diabetes and pregnant women; however, specific host factors responsible for increased GBS susceptibility in these ...
Kathryn A. Patras +9 more
doaj +1 more source
Maternal Dietary Inflammatory Index and Biomarkers of Inflammation at Birth
Maternal &Child Nutrition, EarlyView.ABSTRACT We evaluated the association between the inflammatory potential of the maternal diet during pregnancy and levels of inflammatory biomarkers measured in cord blood and maternal serum at birth. Dietary inflammatory potential was calculated using the energy‐adjusted dietary inflammatory index (E‐DII) in the French EDEN and ELFE birth cohorts ...
Courtney Dow +9 more
wiley +1 more source
PLoS ONE, 2011 The extensive world-wide morbidity and mortality caused by influenza A viruses highlights the need for new insights into the host immune response and novel treatment approaches. Cationic Host Defense Peptides (CHDP, also known as antimicrobial peptides),
Peter G Barlow +7 more
doaj +1 more source
Mapping the omics landscape for peri‐implant diseases: A scoping review
Periodontology 2000, EarlyView.Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng +5 more
wiley +1 more source
Translating gut microbiome research into therapies for type 1 diabetes
Experimental Physiology, EarlyView.Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok +2 more
wiley +1 more source
Cathelicidin Concentration by Age.
, 2016 There was a significant positive correlation between age and cathelicidin concentration (ρ = 0.236, p = 0.005); ρ value represents Spearman correlation.
Bruce W. Hollis (191270) +8 more
core +1 more source
Effects of cathelicidin on coagulation and venous thromboembolism [PDF]
, 2023 Venous thromboembolism is a common vascular disease with high mortality and morbidity. Virchow triad (reduced blood flow velocity, hypercoagulability and endothelial activation) are still considered main pathophysiological factors in the development of ...
Zhang, Qing
core