Results 81 to 90 of about 24,735 (220)

Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment-In vivo studies.

PLoS ONE, 2021
Cathelicidin (CRAMP) is a defence peptide with a wide range of biological responses including antimicrobial, immunomodulatory and wound healing. Due to its original properties the usefulness of CRAMP in the treatment of pulmonary fibrosis was assessed in
Marta Kinga Lemieszek, Katarzyna Sawa-Wejksza, Marcin Golec, Jacek Dutkiewicz, Jacek Zwoliński, Janusz Milanowski   +5 more
doaj   +1 more source

Maternal Dietary Inflammatory Index and Biomarkers of Inflammation at Birth

Maternal &Child Nutrition, EarlyView.
ABSTRACT We evaluated the association between the inflammatory potential of the maternal diet during pregnancy and levels of inflammatory biomarkers measured in cord blood and maternal serum at birth. Dietary inflammatory potential was calculated using the energy‐adjusted dietary inflammatory index (E‐DII) in the French EDEN and ELFE birth cohorts ...
Courtney Dow, Rosalie Delvert, Blandine de Lauzon‐Guillain, Judith van der Waerden, Laetitia Davidovic, Olfa Khalfallah, Susana Barbosa, Marie‐Aline Charles, Cédric Galera, Barbara Heude   +9 more
wiley   +1 more source

Cathelicidin in Urinary Tract Diseases: Diagnostic, Prognostic and Therapeutic Potential of an Evolutionary Conserved Antimicrobial Protein

Medicina
Despite being one of the most common infectious diseases, urinary tract infections (UTIs) still represent a challenge for clinicians to diagnose and treat, especially in the era of growing antibiotic resistance among uropathogenic bacteria.
Iva Sorić Hosman, Andrea Cvitković Roić, Ivana Vuković Brinar, Tonko Gulin, Marijana Ćorić, Dunja Rogić, Ana Lončar Vrančić, Lovro Lamot   +7 more
doaj   +1 more source

Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism

Molecular Therapy: Oncolytics, 2019
The antimicrobial peptide cathelicidin inhibits development of colitis-associated colon cancer. However, the role of cathelicidin in colon cancer metastasis remains unknown.
Jiani Wang, Michelle Cheng, Ivy K.M. Law, Christina Ortiz, Mingjun Sun, Hon Wai Koon   +5 more
doaj   +1 more source

The seasonality of tuberculosis, sunlight, vitamin D, and household crowding. [PDF]

, 2014
BACKGROUND: Unlike other respiratory infections, tuberculosis diagnoses increase in summer. We performed an ecological analysis of this paradoxical seasonality in a Peruvian shantytown over 4 years. METHODS: Tuberculosis symptom-onset and diagnosis dates
Adams, Akhtar, Ane-Anyangwe, Anibarro, Arnedo-Pena, Baker, C. A. Evans, C. Jongkaewwattana, Chew, Dowling, Drucker, E. S. Ramos, Ford, G. Sandhu, J. J. Lewis, J. S. Friedland, K. Zevallos, Kennel, Liu, Lonnroth, Luquero, M. A. Tovar, M. R. Baldwin, Martineau, Nagayama, Onifade, Parrinello, R. H. Gilman, R. Montoya, Rao, Rook, S. G. Schumacher, Schaaf, Stamp, T. Wingfield, ten Asbroek, Wilkinson, Yang, Yoshiyama   +38 more
core   +2 more sources

Cathelicidin and Calprotectin Are Disparately Altered in Murine Models of Inflammatory Arthritis and Airway Inflammation

Frontiers in Immunology, 2020
Cationic host defense peptides (CHDP) are immunomodulatory molecules that control infections and contribute to immune homeostasis. CHDP such as cathelicidin and calprotectin expression is altered in the arthritic synovium, and in the lungs of asthma and ...
Mahadevappa Hemshekhar, Hadeesha Piyadasa, Hadeesha Piyadasa, Dina Mostafa, Dina Mostafa, Leola N. Y. Chow, Andrew J. Halayko, Andrew J. Halayko, Neeloffer Mookherjee, Neeloffer Mookherjee, Neeloffer Mookherjee   +10 more
doaj   +1 more source

Evaluation of the Cutaneous Immunological Milieu Before and After Treatment With Meglumine Antimoniate in Dogs Naturally Affected by Leishmaniosis due to Leishmania infantum

Veterinary Dermatology, EarlyView.
Background: Canine leishmaniosis (CanL) is a zoonotic disease of variable severity. The typical immune response is driven by an exaggerated humoral immune response. Protective immunity is mediated by pro‐inflammatory cytokines that enhance macrophage leishmanicidal activity. Objective: To evaluate the cutaneous and the systemic immune responses as well
M. Platenik, A. Di Loria, L. Archer, M. Saridomichelakis, A. S. Benvenuto, D. Santoro   +5 more
wiley   +1 more source

Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection

mSphere, 2020
Group B Streptococcus (GBS) causes frequent urinary tract infection (UTI) in susceptible populations, including individuals with type 2 diabetes and pregnant women; however, specific host factors responsible for increased GBS susceptibility in these ...
Kathryn A. Patras, Alison Coady, Priyanka Babu, Samuel R. Shing, Albert D. Ha, Emma Rooholfada, Stephanie L. Brandt, Matthew Geriak, Richard L. Gallo, Victor Nizet   +9 more
doaj   +1 more source

Endogenous cathelicidin production limits inflammation and protective immunity to Mycobacterium avium in mice [PDF]

, 2013
The production of antimicrobial peptides, such as the cathelicidins, plays a prominent role in the innate immune response against microbial pathogens. Cathelicidins are widely distributed amongst living organisms, and the antimicrobial peptides generated
Appelberg, R., Gallo, R. L., Gama, F. M., Rosa, G., Santos, J. C., Silva, João P., Silva-Gomes, S.   +6 more
core   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, Volume 299, Issue 6, Page 670-693, June 2026.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source