Results 71 to 80 of about 17,552 (216)

Cathelicidin-3 Associated With Serum Extracellular Vesicles Enables Early Diagnosis of a Transmissible Cancer

, 2022
The identification of practical early diagnostic biomarkers is a cornerstone of improved prevention and treatment of cancers. Such a case is devil facial tumor disease (DFTD), a highly lethal transmissible cancer afflicting virtually an entire species ...
Richard Wilson (308436), Ruth J Pye (12497416), Julian Ratcliffe (9475931), Eduard Willms (9491645), Rodrigo Hamede (159820), Menna E Jones (5926013), Manuel Ruiz-Aravena (5926010), A Bruce Lyons (12497422), Barrett W Wolfe (12497419), Andrew Hill (9487466), Camila Espejo (5926016), Gregory M Woods (4862533)   +11 more
core   +1 more source

Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease

Journal of Inflammation Research, 2021
Paulina Krawiec, Elżbieta Pac-Kożuchowska Department of Pediatrics and Gastroenterology, Medical University of Lublin, Lublin, PolandCorrespondence: Paulina KrawiecDepartment of Pediatrics and Gastroenterology, Medical University of Lublin, Racławickie 1,
Krawiec P, Pac-Kożuchowska E
doaj  

A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea

EMBO Molecular Medicine, 2021
Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC1 signaling is hyperactivated in the skin, especially in the epidermis, of both rosacea patients and a ...
Zhili Deng, Mengting Chen, Yingzi Liu, San Xu, Yuyan Ouyang, Wei Shi, Dan Jian, Ben Wang, Fangfen Liu, Jinmao Li, Qian Shi, Qinqin Peng, Ke Sha, Wenqin Xiao, Tangxiele Liu, Yiya Zhang, Hongbing Zhang, Qian Wang, Lunquan Sun, Hongfu Xie, Ji Li   +20 more
doaj   +1 more source

Hidradenitis suppurativa skin microbiome: In‐depth analysis and modulation by systemic therapies

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Hidradenitis suppurativa skin exhibits profound dysbiosis, characterized by the depletion of homeostatic commensals and expansion of anaerobic pathogens. Longitudinal evaluation reveals that while systemic antibiotics successfully reverse HS dysbiosis, biologics (adalimumab and secukinumab) fail to clear pathogens despite clinical healing.
Yacine Amar, Diana Baumann, Sebastian Niedermeier, Rafaela L. Silva, Susanne Walch, Michael Schloter, Martin Köberle, Tilo Biedermann, Thomas Volz   +8 more
wiley   +1 more source

Cathelicidin in Urinary Tract Diseases: Diagnostic, Prognostic and Therapeutic Potential of an Evolutionary Conserved Antimicrobial Protein

Medicina
Despite being one of the most common infectious diseases, urinary tract infections (UTIs) still represent a challenge for clinicians to diagnose and treat, especially in the era of growing antibiotic resistance among uropathogenic bacteria.
Iva Sorić Hosman, Andrea Cvitković Roić, Ivana Vuković Brinar, Tonko Gulin, Marijana Ćorić, Dunja Rogić, Ana Lončar Vrančić, Lovro Lamot   +7 more
doaj   +1 more source

Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism

Molecular Therapy: Oncolytics, 2019
The antimicrobial peptide cathelicidin inhibits development of colitis-associated colon cancer. However, the role of cathelicidin in colon cancer metastasis remains unknown.
Jiani Wang, Michelle Cheng, Ivy K.M. Law, Christina Ortiz, Mingjun Sun, Hon Wai Koon   +5 more
doaj   +1 more source

Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment-In vivo studies.

PLoS ONE, 2021
Cathelicidin (CRAMP) is a defence peptide with a wide range of biological responses including antimicrobial, immunomodulatory and wound healing. Due to its original properties the usefulness of CRAMP in the treatment of pulmonary fibrosis was assessed in
Marta Kinga Lemieszek, Katarzyna Sawa-Wejksza, Marcin Golec, Jacek Dutkiewicz, Jacek Zwoliński, Janusz Milanowski   +5 more
doaj   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Bivariate Analysis between Cathelicidin and Categorical Variables.

, 2016
Bivariate Analysis between Cathelicidin and Categorical Variables.
Bruce W. Hollis (191270), Judith R. Shary (2735590), Carol L. Wagner (2735581), Taylor M. Stukes (2735587), Wei Wei (21173), Myla D. Ebeling (2735584), Frank S. Shary (2735575), Kaleena B. Dezsi (2735578), Nina E. Forestieri (2735572)   +8 more
core   +1 more source

Cathelicidins in the Tasmanian devil (Sarcophilus harrisii) [PDF]

Scientific Reports, 2016
AbstractTasmanian devil joeys, like other marsupials, are born at a very early stage of development, prior to the development of their adaptive immune system, yet survive in a pathogen-laden pouch and burrow. Antimicrobial peptides, called cathelicidins, which provide innate immune protection during early life, are expressed in the pouch lining, skin ...
Peel, E., Cheng, Y., Djordjevic, J. T., Fox, S., Sorrell, T. C., Belov, K.   +5 more
openaire   +5 more sources