Results 71 to 80 of about 16,196 (213)
MedicinaDespite being one of the most common infectious diseases, urinary tract infections (UTIs) still represent a challenge for clinicians to diagnose and treat, especially in the era of growing antibiotic resistance among uropathogenic bacteria.
Iva Sorić Hosman +7 more
doaj +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala +14 more
wiley +1 more source
DataSheet1_Wound healing mechanism of antimicrobial peptide cathelicidin-DM.pdf
, 2022 Background and Purpose: Chronic wound infections and the development of antibiotic resistance are serious clinical problems that affect millions of people worldwide.
Zhizhi Chen (2209429) +6 more
core +1 more source
Cathelicidin – A Novel Potential Marker of Pediatric Inflammatory Bowel Disease
Journal of Inflammation Research, 2021 Paulina Krawiec, Elżbieta Pac-Kożuchowska Department of Pediatrics and Gastroenterology, Medical University of Lublin, Lublin, PolandCorrespondence: Paulina KrawiecDepartment of Pediatrics and Gastroenterology, Medical University of Lublin, Racławickie 1,
Krawiec P, Pac-Kożuchowska E
doaj
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Molecules, 2023 Antimicrobial peptides (AMPs) hold promise as novel therapeutics in the fight against multi-drug-resistant pathogens. Cathelicidin-PY (NH2-RKCNFLCKLKEKLRTVITSHIDKVLRPQG-COOH) is a 29-residue disulfide-cyclised antimicrobial peptide secreted as an innate ...
Shama Dissanayake +5 more
doaj +1 more source
Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
The role of cathelicidins in neutrophil biology
Journal of Leukocyte BiologyAbstract Despite their relatively short lifespan, neutrophils are tasked with counteracting pathogens through various functions, including phagocytosis, production of reactive oxygen species, neutrophil extracellular traps (NETs), and host defense peptides.
Grace Yoon +4 more
openaire +2 more sources
Cathelicidin Concentration by Age.
, 2016 There was a significant positive correlation between age and cathelicidin concentration (ρ = 0.236, p = 0.005); ρ value represents Spearman correlation.
Bruce W. Hollis (191270) +8 more
core +1 more source
A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea
EMBO Molecular Medicine, 2021 Rosacea is a chronic inflammatory skin disorder whose pathogenesis is unclear. Here, several lines of evidence were provided to demonstrate that mTORC1 signaling is hyperactivated in the skin, especially in the epidermis, of both rosacea patients and a ...
Zhili Deng +20 more
doaj +1 more source