Results 51 to 60 of about 16,196 (213)

Hubungan Kadar Vitamin D dan Cathelicidin Plasma dengan Kejadian Infeksi Tuberkulosis pada Anak dengan Kontak BTA Positif

open access: yesSari Pediatri, 2016
Latar belakang. Vitamin D dan cathelicidin berperan penting dalam sistem imun alamiah terhadap kuman tuberkulosis. Vitamin D memediasi sintesis cathelicidin, melalui ekspresi vitamin D nuclear reseptor (VDR) sehingga cathelicidin dapat membunuh kuman ...
Lola Lusita   +2 more
doaj   +1 more source

The host-defence peptide cathelicidin is critical for the development of pathogenic Th17 responses in multiple sclerosis and experimental autoimmune encephalomyelitis

open access: yes, 2022
Multiple sclerosis (MS) is a highly prevalent demyelinating autoimmune condition; the mechanisms regulating its severity and progression are unclear.
Smith, Katie Jane
core   +1 more source

High expression of antimicrobial peptides cathelicidin-BF in Pichia pastoris and verification of its activity

open access: yesFrontiers in Microbiology, 2023
Antibacterial peptides are endogenous polypeptides produced by multicellular organisms to protect the host against pathogenic microbes, they show broad spectrum antimicrobial activities against various microorganisms and possess low propensity for ...
Xufeng Dong   +5 more
doaj   +1 more source

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

open access: yesAdvanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu   +5 more
wiley   +1 more source

Cathelicidins Link the Endocrine and Immune Systems [PDF]

open access: yesCell Host & Microbe, 2010
Cathelicidin peptides play key roles in host responses to infection. Radek and colleagues (2010) demonstrate that the nicotinic acetylcholine system, activated during stress, suppresses production of mouse cathelicidin, increasing host susceptibility to the pathogen Staphylococcus aureus.
Mayer, Matthew L., Hancock, Robert E.W.
openaire   +2 more sources

Vitamin D, innate immunity and outcomes in community acquired pneumonia

open access: yes, 2011
We investigated the associations between vitamin D status, the antimicrobial peptides cathelicidin and beta defensin-2 and outcomes in community acquired pneumonia.
Karalus, Noel   +9 more
core   +1 more source

Immunomodulatory Role of Cathelicidin at Colonic Epithelium

open access: yes, 2020
Cathelicidin, a small, cationic and amphiphilic host defense peptide, is expressed by hematopoietic and non-hematopoietic cells. Initially considered an antimicrobial, cathelicidin are more than simply natural antibiotics.
Holani, Ravi
core   +1 more source

Biofilm Exoproteins From Staphylococcus Species Impede Re‐Epithelialization of Nasal Epithelial Cells During Wound Healing and Cease Ciliary Beat Frequency

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Chronic rhinosinusitis (CRS) is an inflammatory disease with many different contributing factors, including bacterial infection. CRS patients are typically managed with medical therapies; however, these treatments frequently fail, leaving surgery as the only viable option.
Sintayehu Ambachew   +8 more
wiley   +1 more source

Identification of a novel cathelicidin gene in the rainbow trout, Oncorhynchus mykiss

open access: yes, 2005
We report the cloning of a novel antimicrobial peptide gene, termed rtCATH_1, found in the rainbow trout, Oncorhynchus mykiss. The predicted 216-residue rtCATH_1 prepropeptide consists of three domains: a 22-residue signal peptide, a 128-residue cathelin-
Zou, J   +5 more
core   +1 more source

Cathelicidins: family of antimicrobial peptides. A review [PDF]

open access: yesMolecular Biology Reports, 2012
Cathelicidins are small, cationic, antimicrobial peptides found in humans and other species, including farm animals (cattle, horses, pigs, sheep, goats, chickens, rabbits and in some species of fish). These proteolytically activated peptides are part of the innate immune system of many vertebrates.
Kościuczuk, EM   +8 more
openaire   +2 more sources

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