Results 51 to 60 of about 24,735 (220)
Cathelicidin promotes liver repair after acetaminophen-induced liver injury in mice
JHEP Reports, 2023 Background & Aims: Acetaminophen (APAP)-induced acute liver injury (AILI) is a leading cause of acute liver failure (ALF). N-acetylcysteine (NAC) is only effective within 24 h after APAP intoxication, raising an urgent need for alternative approaches
Tingting Zhai +6 more
doaj +1 more source
Human Cathelicidin Production by the Cervix
PLoS ONE, 2014 hCAP18/LL-37 is the sole human cathelicidin; a family of host defence peptides with key roles in innate host defence. hCAP18/LL-37 is expressed primarily by neutrophils and epithelial cells, but its production and function in the lower genital tract is largely uncharacterised.
Frew, Lorraine +7 more
openaire +6 more sources
Snake Venom Cathelicidins as Natural Antimicrobial Peptides [PDF]
Frontiers in Pharmacology, 2019 Bioactive small molecules isolated from animals, plants, fungi and bacteria, including natural antimicrobial peptides, have shown great therapeutic potential worldwide. Among these peptides, snake venom cathelicidins are being widely exploited, because the variation in the composition of the venom reflects a range of biological activities that may be ...
Elizângela de Barros +14 more
openaire +4 more sources
Cathelicidin impact on inflammatory cells.
Central-European journal of immunology, 2015 Cathelicidins, like other antimicrobial peptides, exhibit direct antimicrobial activities against a broad spectrum of microbes, including both Gram-positive and Gram-negative bacteria, enveloped viruses, and fungi. These host-derived peptides kill the invaded pathogens by perturbing their cell membranes and can neutralize biological activities of ...
Agier, Justyna +2 more
openaire +3 more sources
Frontiers in Cellular and Infection Microbiology, 2017 Cathelicidin-BF, derived from the banded krait (Bungarus fasciatus), is a typically cationic, amphiphilic and α-helical antimicrobial peptide (AMP) with 30 amino acids that exerts powerful effects on multidrug-resistant (MDR) clinical isolates, including
Cunbao Liu +3 more
doaj +1 more source
Subversion of host innate immunity by uropathogenic Escherichia coli [PDF]
, 2016 Uropathogenic Escherichia coli (UPEC) cause the majority of community-onset urinary tract infections (UTI) and represent a major etiologic agent of healthcare-associated UTI.
Cavalieri +5 more
core +3 more sources
Sari Pediatri, 2016 Latar belakang. Vitamin D dan cathelicidin berperan penting dalam sistem imun alamiah terhadap kuman tuberkulosis. Vitamin D memediasi sintesis cathelicidin, melalui ekspresi vitamin D nuclear reseptor (VDR) sehingga cathelicidin dapat membunuh kuman ...
Lola Lusita +2 more
doaj +1 more source
Immunomodulatory Properties of Defensins and Cathelicidins [PDF]
, 2006 Host defence peptides are a conserved component of the innate immune response in all complex life forms. In humans, the major classes of host defence peptides include the alpha- and beta-defensins and the cathelicidin, hCAP-18/LL-37. These peptides are expressed in the granules of neutrophils and by a wide variety of tissue types.
Bowdish, D. M. E. +2 more
openaire +2 more sources
Activity of Cathelicidin Peptides against Simkania negevensis [PDF]
International Journal of Peptides, 2011 The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S.
DONATI, MANUELA +8 more
openaire +3 more sources
Frontiers in Microbiology, 2023 Antibacterial peptides are endogenous polypeptides produced by multicellular organisms to protect the host against pathogenic microbes, they show broad spectrum antimicrobial activities against various microorganisms and possess low propensity for ...
Xufeng Dong +5 more
doaj +1 more source