Results 41 to 50 of about 16,196 (213)
مجله كليه طب الكندي, 2023 Background: Vitamin D improves innate immunity by enhancing the expression of antimicrobial peptides. The antimicrobial action of cathelicidin is widespread and effective against cariogenic bacteria.
Narjes M. Alhelfi, Nibal M. Hobi
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Immunomodulatory Properties of Defensins and Cathelicidins [PDF]
, 2006 Host defence peptides are a conserved component of the innate immune response in all complex life forms. In humans, the major classes of host defence peptides include the alpha- and beta-defensins and the cathelicidin, hCAP-18/LL-37. These peptides are expressed in the granules of neutrophils and by a wide variety of tissue types.
Bowdish, D. M. E. +2 more
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Cathelicidin impact on inflammatory cells
Central European Journal of Immunology, 2015 Cathelicidins, like other antimicrobial peptides, exhibit direct antimicrobial activities against a broad spectrum of microbes, including both Gram-positive and Gram-negative bacteria, enveloped viruses, and fungi. These host-derived peptides kill the invaded pathogens by perturbing their cell membranes and can neutralize biological activities of ...
Agier, Justyna +2 more
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Медицинская иммунология, 2018 Granulysin and cathelicidin, the cytolytic molecules of innate immune system are important protective factors during infection with Mycobacterium tuberculosis. We present original data concerning high levels of granulysin and cathelicidin among the group
M. M. (Jr) Averbakh +3 more
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The roles of vitamin D and cathelicidin in type 1 diabetes susceptibility
Endocrine Connections, 2021 Type 1 diabetes has an increasingly greater incidence and prevalence with no cure available. Vitamin D supplementation is well documented to reduce the risk of developing type 1 diabetes.
Cecília Cristelo +3 more
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Cathelicidin attenuates hyperoxia-induced kidney injury in newborn rats
Renal Failure, 2019 Aim: Supplemental oxygen is often used to treat neonates with respiratory disorders. Human and animal studies have demonstrated that neonatal hyperoxia increases oxidative stress and induces damage and collagen deposition in kidney during the perinatal ...
Hsiu-Chu Chou, Chung-Ming Chen
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Streptococcal M1 Strikes by Neutralizing Cathelicidins [PDF]
Cell Host & Microbe, 2015 Virulent group A streptococci have become a serious threat, with the emergence of the hypervirulent lineage M1T1. In this issue of Cell Host & Microbe, LaRock et al. (2015), uncover a role for the streptococcal M1 protein in neutralizing a key human antimicrobial peptide, cathelicidin.
Henriques-Normark, Birgitta +1 more
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Frontiers in Cellular and Infection Microbiology, 2017 Cathelicidin-BF, derived from the banded krait (Bungarus fasciatus), is a typically cationic, amphiphilic and α-helical antimicrobial peptide (AMP) with 30 amino acids that exerts powerful effects on multidrug-resistant (MDR) clinical isolates, including
Cunbao Liu +3 more
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Cathelicidin promotes liver repair after acetaminophen-induced liver injury in mice
JHEP Reports, 2023 Background & Aims: Acetaminophen (APAP)-induced acute liver injury (AILI) is a leading cause of acute liver failure (ALF). N-acetylcysteine (NAC) is only effective within 24 h after APAP intoxication, raising an urgent need for alternative approaches
Tingting Zhai +6 more
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Expression of Cathelicidin in Human Salivary Glands [PDF]
Archives of Otolaryngology–Head & Neck Surgery, 2003 Salivary secretions play a critical role in maintaining oral health via innate host defense mechanisms and secretion of secretory IgA. One of the antimicrobial peptides, LL-37, is the only cathelicidin protein that has yet been identified in humans. Cathelicidins are a family of peptides thought to provide an innate defensive barrier against a variety ...
Jeong-Su, Woo +5 more
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