Results 31 to 40 of about 16,196 (213)

Evolution of the Primate Cathelicidin [PDF]

Journal of Biological Chemistry, 2006
n ...
Zelezetsky, Igor, Pontillo, Alessandra, Puzzi, Luca, Antcheva, Nikolinka, Segat, Ludovica, Pacor, Sabrina, Crovella, Sergio, Tossi, Alessandro   +7 more
openaire   +2 more sources

Cathelicidins Modulate TLR-Activation and Inflammation [PDF]

Frontiers in Immunology, 2020
Cathelicidins are short cationic peptides that are part of the innate immune system. At first, these peptides were studied mostly for their direct antimicrobial killing capacity, but nowadays they are more and more appreciated for their immunomodulatory functions.
Maaike R. Scheenstra, Roel M. van Harten, Edwin J. A. Veldhuizen, Henk P. Haagsman, Maarten Coorens, Maarten Coorens   +5 more
openaire   +4 more sources

Cathelicidins from the bullfrog Rana catesbeiana provides novel template for peptide antibiotic design.

PLoS ONE, 2014
Cathelicidins, a class of gene-encoded effector molecules of vertebrate innate immunity, provide a first line of defense against microbial invasions. Although cathelicidins from mammals, birds, reptiles and fishes have been extensively studied, little is
Guiying Ling, Jiuxiang Gao, Shumin Zhang, Zeping Xie, Lin Wei, Haining Yu, Yipeng Wang   +6 more
doaj   +1 more source

Cathelicidin-DM is an Antimicrobial Peptide from Duttaphrynus melanostictus and Has Wound-Healing Therapeutic Potential

, 2020
Antimicrobial peptides (AMPs) are a class of templates with application potential for drug development. Amphibians are important sources of AMPs. Duttaphrynus melanostictus is the main source of traditional Chinese medicine “Chansu”, which has anti ...
Chao Li (145513), Zijun Chen (286584), Ying Luo (381053), A-Mei Zhang (157343), Yaoqiang Shi (8708502), Yi Sun (118759), Xue-shan Xia (8708505), Yuzhu Song (4379782), Mei Wang (130842)   +8 more
core   +1 more source

A cross sectional analysis of the role of the antimicrobial peptide cathelicidin in lung function impairment within the ALIVE cohort.

PLoS ONE, 2014
BackgroundVitamin D deficiency is associated with reduced lung function. Cathelicidin, an antimicrobial peptide regulated by vitamin D, plays a role within the innate immune system.
Allison A Lambert, Gregory D Kirk, Jacquie Astemborski, Enid R Neptune, Shruti H Mehta, Robert A Wise, M Bradley Drummond   +6 more
doaj   +1 more source

Cathelicidin Attenuates Hyperoxia-Induced Lung Injury by Inhibiting Ferroptosis in Newborn Rats

Antioxidants, 2022
High oxygen concentrations are often required to treat newborn infants with respiratory distress but have adverse effects, such as increased oxidative stress and ferroptosis and impaired alveolarization.
Hsiu-Chu Chou, Chung-Ming Chen
doaj   +1 more source

Antifungal Activity of Human Cathelicidin LL-37, a Membrane Disrupting Peptide, by Triggering Oxidative Stress and Cell Cycle Arrest in Candida auris

Journal of Fungi, 2022
Candida auris, an evolving multidrug-resistant pathogenic yeast, is known for causing severe invasive infections associated with high mortality rates in hospitalized individuals. Distinct from other Candida species, C.
Irfan A. Rather, Jamal S. M. Sabir, Amer H. Asseri, Sajad Ali   +3 more
doaj   +1 more source

Human Cathelicidin Production by the Cervix

PLoS ONE, 2014
hCAP18/LL-37 is the sole human cathelicidin; a family of host defence peptides with key roles in innate host defence. hCAP18/LL-37 is expressed primarily by neutrophils and epithelial cells, but its production and function in the lower genital tract is largely uncharacterised.
Frew, Lorraine, Makieva, Sofia, McKinlay, Andrew T M, McHugh, Brian J, Doust, Ann, Norman, Jane E, Davidson, Donald J, Stock, Sarah J   +7 more
openaire   +6 more sources

Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis [PDF]

, 2009
Antimicrobial peptides (AMPs) are strongly expressed in lesional skin in psoriasis and play an important role as proinflammatory "alarmins" in this chronic skin disease.
Koglin, Sarah, Ulrich Zügel, Thomas Ruzicka, Büchau Amanda, Dombrowski, Yvonne, Zügel, Ulrich, Steinmeyer, Andreas, Jürgen Schauber, Schauber, Jürgen, Büchau, Amanda, Sarah Koglin, Steinmeyer Andreas, Bradac, Eva, Mark Peric, Schauber Jürgen, Koglin Sarah, Amanda Büchau, Zügel Ulrich, Yvonne Dombrowski, Eva Bradac, Katrin Gross, Peric Mark, Gross, Katrin, Dombrowski Yvonne, Peric, Mark, Andreas Steinmeyer, Dombrowski, Yvonne; id_orcid, Bradac Eva, Groß Katrin, Ruzicka, Thomas, Ruzicka Thomas   +30 more
core   +1 more source

Plasma cathelicidin and longitudinal lung function in current and former smokers.

PLoS ONE, 2019
IntroductionCathelicidin (also known as LL-37 in humans) is an antimicrobial peptide secreted by epithelial and immune cells and regulated by vitamin D. The immunological roles of cathelicidin make it a putative biomarker to identify individuals at risk ...
Robert M Burkes, Jacquie Astemborski, Allison A Lambert, Todd T Brown, Robert A Wise, Gregory D Kirk, M Bradley Drummond   +6 more
doaj   +1 more source