Results 31 to 40 of about 24,735 (220)

Genetic diversity of Japanese quail cathelicidins

open access: yesPoultry Science, 2021
Japanese quail is a low-fat, meat-bird species exhibiting high disease resistance. Cathelicidins (CATHs) are host defense peptides conserved across numerous vertebrate species that play an important role in innate immunity. The activity of host defense peptides can be affected by amino acid substitutions.
Taichiro Ishige   +4 more
openaire   +3 more sources

A cross sectional analysis of the role of the antimicrobial peptide cathelicidin in lung function impairment within the ALIVE cohort.

open access: yesPLoS ONE, 2014
BackgroundVitamin D deficiency is associated with reduced lung function. Cathelicidin, an antimicrobial peptide regulated by vitamin D, plays a role within the innate immune system.
Allison A Lambert   +6 more
doaj   +1 more source

Cathelicidin Attenuates Hyperoxia-Induced Lung Injury by Inhibiting Ferroptosis in Newborn Rats

open access: yesAntioxidants, 2022
High oxygen concentrations are often required to treat newborn infants with respiratory distress but have adverse effects, such as increased oxidative stress and ferroptosis and impaired alveolarization.
Hsiu-Chu Chou, Chung-Ming Chen
doaj   +1 more source

Destabilization of α-helical structure in solution improves bactericidal activity of antimicrobial peptides: Opposing effects on bacterial and viral targets [PDF]

open access: yes, 2016
We have previously examined the mechanism of antimicrobial peptides on the outer membrane of vaccinia virus. Here we show that the formulation of peptides LL37 and magainin-2B amide in polysorbate 20 (Tween-20™) results in greater reductions in virus ...
Beck, Konrad   +4 more
core   +2 more sources

Antifungal Activity of Human Cathelicidin LL-37, a Membrane Disrupting Peptide, by Triggering Oxidative Stress and Cell Cycle Arrest in Candida auris

open access: yesJournal of Fungi, 2022
Candida auris, an evolving multidrug-resistant pathogenic yeast, is known for causing severe invasive infections associated with high mortality rates in hospitalized individuals. Distinct from other Candida species, C.
Irfan A. Rather   +3 more
doaj   +1 more source

Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus. [PDF]

open access: yes, 2014
Anthracimycin is a recently discovered novel marine-derived compound with activity against Bacillus anthracis. We tested anthracimycin against an expanded panel of Staphylococcus aureus strains in vitro and in vivo. All strains of S.
Cunningham, Mark L   +12 more
core   +1 more source

Streptococcal M1 Strikes by Neutralizing Cathelicidins [PDF]

open access: yesCell Host & Microbe, 2015
Virulent group A streptococci have become a serious threat, with the emergence of the hypervirulent lineage M1T1. In this issue of Cell Host & Microbe, LaRock et al. (2015), uncover a role for the streptococcal M1 protein in neutralizing a key human antimicrobial peptide, cathelicidin.
Henriques-Normark, Birgitta   +1 more
openaire   +2 more sources

Vitamin D and immunity [PDF]

open access: yes, 2014
Vitamin D deficiency has been linked to an increased risk of a wide range of adverse health outcomes. The active form of vitamin D has an important role in calcium metabolism and in bone mineralisation, but the evidence for other health outcomes is mixed,
Geldenhuys, Sian   +3 more
core   +1 more source

Influence of Vitamin D Deficiency on the Level of Salivary cathelicidin LL-37 in relation to Dental Caries Experience: A Case-Control Study

open access: yesمجله كليه طب الكندي, 2023
Background: Vitamin D improves innate immunity by enhancing the expression of antimicrobial peptides. The antimicrobial action of cathelicidin is widespread and effective against cariogenic bacteria.
Narjes M. Alhelfi, Nibal M. Hobi
doaj   +1 more source

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