Results 91 to 100 of about 16,196 (213)

Vitamin D receptor signaling in inflammatory senescence–associated skin aging: Mechanisms and therapeutic potentials

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Vitamin D receptor (VDR) signaling is implicated in inflammatory senescence‐associated skin aging, a growing health concern in aging populations where cellular senescence and chronic inflammation converge to create complex pathophysiological conditions.
Liancheng Guan, Fan Yang, Meijuan Li, Yujia Chen, Zexin Zhao, Hongxia Li, Deping Luo, Qian Li, Yunzhi Chen   +8 more
wiley   +1 more source

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, Volume 6, Issue 3, June 2026.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source

Nasal cathelicidin is expressed in early life and is increased during mild, but not severe respiratory syncytial virus infection

Scientific Reports
Respiratory syncytial virus is the major cause of acute lower respiratory tract infections in young children, causing extensive mortality and morbidity globally, with limited therapeutic or preventative options.
Sofia Sintoris, Justyna M. Binkowska, Jonathan L. Gillan, Roy P. Zuurbier, Jonathan Twynam-Perkins, Maartje Kristensen, Lauren Melrose, Paula Lusaretta Parga, Alicia Ruiz Rodriguez, Mei Ling Chu, Sara R. van Boeckel, Joanne G. Wildenbeest, Dawn M. E. Bowdish, Andrew J. Currie, Ryan S. Thwaites, Jurgen Schwarze, Marlies A. van Houten, James P. Boardman, Steve Cunningham, Debby Bogaert, Donald J. Davidson   +20 more
doaj   +1 more source

Avian host defense cathelicidins: structure, expression, biological functions, and potential therapeutic applications

Poultry Science, 2020
Host defense peptides (HDP) are multifunctional effectors of the innate immune system, which has antimicrobial and pleiotropic immunomodulatory functions.
Yingjie Wang, Min Wang, Anshan Shan, Xingjun Feng   +3 more
doaj   +1 more source

Engineered Bacillus subtilis regulates intestinal barrier in ETEC K88‐infected piglets and modulates miR‐1250‐5p/NFκB pathway in IPEC‐J2

iMetaOmics, Volume 3, Issue 2, June 2026.
Upon enterotoxigenic Escherichia coli (ETEC) K88 infection, intestinal barrier function is disrupted with compromised tight junctions, accompanied by an exacerbated inflammatory response, proliferation of pathogenic Escherichia, and depletion of beneficial Lactobacillus paralimentarius.
Chaoyue Wen, Hong Zhang, Qiuping Guo, Yehui Duan, Sisi Chen, Mengmeng Han, Leli Wang, Le Huang, Yuankun Deng, Fengna Li, Yizhen Wang, Mingliang Jin   +11 more
wiley   +1 more source

Thermal tolerance of cathelicidin-RC1.

, 2014
Thermal tolerance of cathelicidin-RC1 was determined by measuring MICs after incubation at different temperatures. Cathelicidin-RC1 solution (2 mg/ml, dissolved in sterile deionized water) was incubated at different temperatures (4, 20, 37, 50, 70, and ...
Guiying Ling (543925), Zeping Xie (543927), Shumin Zhang (187205), Lin Wei (70005), Haining Yu (227578), Jiuxiang Gao (543926), Yipeng Wang (9800)   +6 more
core   +1 more source

Bronchoalveolar Lavage and Plasma Cathelicidin Response to 25-Hydroxy Vitamin D Supplementation: A Pilot Study.

, 2021
INTRODUCTION: Cathelicidin is a vitamin D-regulated, antimicrobial peptide involved in the innate immune response of the airways. Reduced plasma cathelicidin concentrations are independently associated with worse pulmonary outcomes in current and former ...
Burkes, Robert M, Mock, Jason R, Hansel, Nadia N, Drummond, M Bradley, Liu, Mark C, Brown, Todd T, Sanders, Emily C, Wise, Robert A   +7 more
core   +2 more sources

The Assessment of Vitamin D, Antimicrobial Peptides and Procalcitonin in Bronchiectasis

, 2014
My research investigated the distribution of antimicrobial peptides (cathelicidin and β-defensin 2), vitamin D and the inflammatory marker procalcitonin, between systemic and localised respiratory levels in stable bronchiectasis patients.
Gartner, Sarah Nicole
core  

Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin

, 2009
SummaryAutophagy and vitamin D3-mediated innate immunity have been shown to confer protection against infection with intracellular Mycobacterium tuberculosis.
Jin, Hyo Sun, Jo, Eun-Kyeong, Kim, Kwang-Kyu, Lee, Zee-Won, Lee, Sang-Hee, Yuk, Jae-Min, Lee, Hye-Mi, Shin, Dong-Min, Yang, Chul-Su, Kim, Jin-Man   +9 more
core   +1 more source

Amniotic fluid cathelicidin in PPROM pregnancies: from proteomic discovery to assessing its potential in inflammatory complications diagnosis.

PLoS ONE, 2012
BackgroundPreterm prelabor rupture of membranes (PPROM) complicated by microbial invasion of the amniotic cavity (MIAC) leading to histological chorioamnionitis (HCA) significantly impacts perinatal morbidity.
Vojtech Tambor, Marian Kacerovsky, Marian Kacerovsky, Ctirad Andrys, Ivana Musilova, Helena Hornychova, Lenka Pliskova, Marek Link, Jiri Stulik, Juraj Lenco   +9 more
doaj   +1 more source