Results 291 to 300 of about 191,378 (381)

A novel cysteine cathepsin inhibitor yields macrophage cell death and mammary tumor regression

Oncogene, 2015
Seth J. Salpeter, Y. Pozniak, E. Merquiol, Yael Ben-Nun, Tamar Geiger, Galia Blum   +5 more
semanticscholar   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Bone Marker Proteins in Women With and Without Polycystic Ovary Syndrome. [PDF]

Int J Mol Sci
Atkin BML, Sathyapalan T, Dempsey L, Atkin SL, Butler AE.   +4 more
europepmc   +1 more source

Muscle wasting in cancer cachexia: Mechanisms and the role of exercise

Experimental Physiology, EarlyView.
Abstract Cancer cachexia (CC) is a multifactorial disease marked by a severe and progressive loss of lean muscle mass and characterized further by inflammation and a negative energy/protein balance, ultimately leading to muscle atrophy and loss of muscle tissue.
Zoe P. Libramento, Louisa Tichy, Traci L. Parry   +2 more
wiley   +1 more source

Cathepsins and their involvement in immune responses

Swiss Medical Weekly, 2010
Swiss Medical Weekly
doaj   +1 more source

Mendelian Randomization Analyses Reveal the Causal Effect of Cathepsin Z on the Risk of Different Subtypes of Thyroid Cancer. [PDF]

Int J Endocrinol
Sun SK, Yuan JL.
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Proteomic analysis links truncated tau to lysosome motility, autophagy, and endo-lysosomal dysfunction. [PDF]

Alzheimers Dement
Goniotaki D, Hausherr M, Lynham S, Ale A, Chennell G, Marcotti S, Marcus K, Noble W, Hanger DP, Fraser G, Srivastava DP.   +10 more
europepmc   +1 more source

Cathepsin S and cathepsin L in serum and synovial fluid in rheumatoid arthritis with and without autoantibodies.

Rheumatology, 2015
T. Weitoft, A. Larsson, V. Manivel, J. Lysholm, A. Knight, J. Rönnelid   +5 more
semanticscholar   +1 more source

The central benefit of physiologically induced ketogenic states

The Journal of Physiology, EarlyView.
Abstract figure legend This review describes the association between ketogenic states induced by physiological interventions such as fasting or aerobic exercise, exogenous ketone supply and ketogenic diets, as well as increased cognition through increased activity of brain‐derived neurotrophic factor (BDNF).
Antonia Giacco, Giuseppe Petito, Rosalba Senese, Maria Moreno, Assunta Lombardi, Antonia Lanni, Pieter de Lange   +6 more
wiley   +1 more source