Results 161 to 170 of about 13,268,265 (360)

Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function.

open access: yesCell Metabolism, 2016
H. Moon   +11 more
semanticscholar   +1 more source

Pharmacokinetic and Exposure–Response Modeling Support Body Surface Area‐Based Dosing of Farletuzumab Ecteribulin in Japanese Patients with Solid Tumors

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract The first‐in‐human, Phase 1 Study 101 showed antitumor activity and a tolerable safety profile of farletuzumab ecteribulin in Japanese patients with platinum‐resistant ovarian and non‐small cell lung cancer. A pharmacometric assessment evaluated farletuzumab ecteribulin pharmacokinetics and exposure–response (E‐R) relationships for efficacy ...
Seiichi Hayato   +18 more
wiley   +1 more source

Metformin reverses periodontal destruction caused by experimental periodontitis by inhibiting interleukin‐1β activity

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis is a destructive disease that affects periodontal tissue. While current research focuses on disease management, research on tissue repair remains limited. Metformin, a first‐line medication for diabetes treatment, has positive effects on bone health in nondiabetic patients.
Zhao Wang   +10 more
wiley   +1 more source

Proteomic study on the lymphocytes from pregnant Wistar rat females treated with immunosuppressive regimen

open access: yesClinical and Translational Science, Volume 16, Issue 1, Page 118-127, January 2023., 2023
Abstract Kidney transplantation remains the therapeutic option for patients with end‐stage kidney disease. Current immunosuppressive regimens are efficient in combating acute kidney rejection. However, insights into chronic kidney allograft injury remains limited.
Bartosz Wojciuk   +6 more
wiley   +1 more source

Importance of proteins and mitochondrial changes as freshness indicators in fish muscle post‐mortem

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Evaluating protein and mitochondrial alterations post‐mortem can contribute to determining correlations between fish‐processing parameters and ultimate fish muscle quality. The myofibrillar protein alteration during rigor mortis directly affects the texture of fish muscle.
Nima Hematyar   +2 more
wiley   +1 more source

Assessment of interleukin-6 and cathepsin-B gene expression in breast cancer women

open access: yesEgyptian Journal of Medical Human Genetics
Background Breast cancer (BC) is the most prevalent cancer and the leading cause of cancer-related deaths in women globally. Cysteine protease cathepsin-B has been implicated in various human malignancies and is involved in malignancy progression and ...
Basma A. Ibrahim   +4 more
doaj   +1 more source

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