Results 171 to 180 of about 13,268,265 (360)

Active and Inactive Forms of the Transition-state Analog Protease Inhibitor Leupeptin: Explanation of the Observed Slow Binding of Leupeptin to Cathepsin B and Papain

, 1989
Richard M. Schultz, P. Varma-Nelson, Rafael Aguayo Ortiz, K.A. Kozlowski, Arthur T. Orawski, Peter Pagast, Allen Frankfater   +6 more
openalex   +1 more source

Mosquito Cathepsin B-like Protease Involved in Embryonic Degradation of Vitellin Is Produced as a Latent Extraovarian Precursor [PDF]

, 1999
Wen-Long Cho, Shin-Mei Tsao, Alan R. Hays, Rosemarie Walter, Jeng-Shong Chen, E. S. Snigirevskaya, Alexander S. Raikhel   +6 more
openalex   +1 more source

Cathepsin B: A sellsword of cancer progression.

Cancer Letters, 2019
O. Mijanović, Ana Brankovic, A. Panin, S. Savchuk, P. Timashev, I. Ulasov, M. Lesniak   +6 more
semanticscholar   +1 more source

Inhalable Nano Formulation of Cabazitaxel: A Comparative Study with Intravenous Route

Macromolecular Bioscience, EarlyView.
Nano drug formulation shows no signs of toxicity for IV and INH routes, whereas higher systemic toxicity occurs in free drug formulation in both. Inhalable nano formulation provides higher and longer retention in deep lung regions due to its size and defies rapid systemic absorption in the lungs.
Elif Kaga, Sadik Kaga, Korhan Altunbas, Nurullah Okumus   +3 more
wiley   +1 more source

Suppression of Cathepsins B and L Causes a Proliferation of Lysosomes and the Formation of Meganeurites in Hippocampus [PDF]

, 1997
Eric Bednarski, Charles E. Ribak, Gary Lynch   +2 more
openalex   +1 more source

Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond

Macromolecular Bioscience, EarlyView.
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley   +1 more source

Temporal pattern of cysteine endopeptidase (cathepsin B) expression in cartilage and synovium from rabbit knees with experimental osteoarthritis: gene expression in chondrocytes in response to interleukin-1 and matrix depletion [PDF]

, 1997
Fuad Mehraban, M H Tindal, MaxR. Proffitt, Roland W. Moskowitz   +3 more
openalex   +1 more source

Development of phytotherapeutic nanoformulation containing Gypsophila eriocalyx and its evaluation as a candidate formulation for osteoporosis treatment on human bone marrow stem cells

Phytochemical Analysis, EarlyView.
Abstract Introduction Osteoporosis, one of the common bone diseases, manifests itself as a decrease in bone mass. Recently, the use of medicinal plants in the search for effective and low‐toxicity therapeutics for the prevention or treatment of osteoporosis has become a trending topic.
Sibel Kaymak, Ozan Baris Kurtur, Bahar Gok, Yasemin Budama‐Kilinc, Serda Kecel‐Gunduz, Ebru Özdemir Nath, Murat Kartal   +6 more
wiley   +1 more source

Optical Imaging of Cancer-Related Proteases Using Near-Infrared Fluorescence Matrix Metalloproteinase-Sensitive and Cathepsin B-Sensitive Probes

Theranostics, 2012
Cathepsin B and matrix metalloproteinase (MMP) play key roles in tumor progression by controlled degradation of extracellular matrix. Consequently, these proteases have been attracted in cancer research, and many imaging probes utilizing these proteases ...
Ji Young Yhee, Sun Ah Kim, Heebeom Koo, Sohee Son, Ju Hee Ryu, In-Chan Youn, Kuiwon Choi, Ick Chan Kwon, Kwangmeyung Kim
doaj  

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes, Roberta Coletti, Flore Duranton, Griet Glorieux, Mayra Alejandra Jaimes Campos, Julie Klein, Matthias Ley, Paul Perco, Alexia Sampri, Aviad Tur‐Sinai   +9 more
wiley   +1 more source