Results 181 to 190 of about 13,268,265 (360)

Investigation of the Urinary Peptidome to Unravel Collagen Degradation in Health and Kidney Disease

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Naturally occurring fragments of collagen type I alpha 1 chain (COL1A1) have been previously associated with chronic kidney disease (CKD), with some fragments showing positive and others negative associations. Using urinary peptidome data from healthy individuals (n = 1131) and CKD patients (n = 5585) this aspect was investigated in detail ...
Ioanna K. Mina   +7 more
wiley   +1 more source

Switch of CD4+ T Cell Differentiation from Th2 to Th1 by Treatment with Cathepsin B Inhibitor in Experimental Leishmaniasis [PDF]

open access: bronze, 1998
Yoichi Maekawa   +8 more
openalex   +1 more source

Substrate/propeptide‐derived endo‐epoxysuccinyl peptides as highly potent and selective cathepsin B inhibitors [PDF]

open access: bronze, 1998
Norbert Schaschke   +3 more
openalex   +1 more source

Utilizing Two Electrokinetic Techniques on a Single Device for Detection of Extracellular Vesicle‐Associated Protease Activity

open access: yesSmall, EarlyView.
Protease activity of cancer‐derived extracellular vesicles is quantified using a single microelectrode array in a microfluidic device to create two different electrokinetic‐based analyte collection mechanisms. First, dielectrophoresis is used to recover and purify EVs from plasma followed by electrophoresis to quantify protease activity using cleavable
Ella Stimson   +9 more
wiley   +1 more source

Bioactive food components and their inhibitory actions in multiple platelet pathways

open access: yesJournal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
A comprehensive overview of platelet multifunctional roles in CVD and other diseases and the effects of food components' modulatory effects are described. Abstract In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis ...
Diptimayee Das   +7 more
wiley   +1 more source

Hairpin loop mutations of chicken cystatin have different effects on the inhibition of cathepsin B, cathepsin L and papain [PDF]

open access: bronze, 1995
Ennes A. Auerswald   +5 more
openalex   +1 more source

Understanding of endo/lysosomal escape of nanomaterials in biomedical application

open access: yesSmart Molecules, EarlyView.
This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang   +3 more
wiley   +1 more source

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