Results 211 to 220 of about 122,992 (302)

Genomes of Fasciola hepatica from the Americas reveal colonization with Neorickettsia endobacteria related to the agents of Potomac horse and human Sennetsu fevers [PDF]

, 2017
Choi, Young-Jun, et al.,, Fischer, Peter U, Hallsworth-Pepin, Kymberlie, McNulty, Samantha N, Mitreva, Makedonka, Rosa, Bruce A, Tyagi, Rahul   +7 more
core   +1 more source

Psyllid Cysteine Cathepsins Directly Cleave the Outer Membrane Protein BamD of Citrus Huanglongbing Pathogen

Plant Biotechnology Journal, EarlyView.
ABSTRACT Candidatus Liberibacter asiaticus (CLas), the causative agent of citrus Huanglongbing (HLB), is transmitted by Asian citrus psyllid, Diaphorina citri; however, the role of the insect's immune effectors in defending against CLas remains poorly understood. This study reveals that D.
Yu Du, Yu Bin, Jinhua Yang, Manman Hu, Liqin Jiang, Qiaoling Su, Shiyi Lin, Lanfeng Qu, You Li, Taiyun Wei   +9 more
wiley   +1 more source

Cathepsin B in urological tumors: unraveling its role and therapeutic potential. [PDF]

Discov Oncol
Yan Z, Zheng G, Zou J, Zou X, Chai K, Zhang G.   +5 more
europepmc   +1 more source

Unfolding Plant Defence: Endoplasmic Reticulum Stress Signalling at the Plant‐Pathogen Interface

Plant Biotechnology Journal, EarlyView.
ABSTRACT The endoplasmic reticulum (ER) stress response, a conserved proteostasis network, has emerged as a central hub that reprograms plant immunity during pathogen attack. This review synthesises how plants harness ER‐stress signalling to mount multilayered defences and how pathogens have evolved counterstrategies to subvert these pathways.
Zhe Meng, Shuqin Zheng, Federica Brandizzi, Yiran Liu, Chunlei Li, Congcong Ai, Yujiao Wang, Jiadong Qi, Xiuguo Zhang   +8 more
wiley   +1 more source

Neutral pH-Selective Inhibition of Cytosolic Cathepsin B: A Novel Drug Targeting Strategy for Traumatic Brain Injury and Alzheimer's Disease. [PDF]

ACS Chem Biol
Hook V, Podvin S, Yoon MC, Phan VV, Florio J, Spencer B, Mosier C, Cheng A, Ahuett S, Almaliti J, Gerwick WH, Rissman RA, O'Donoghue AJ.   +12 more
europepmc   +1 more source

A Placenta Derived C-Terminal Fragment of beta-Hemoglobin With Combined Antibacterial and Antiviral Activity

, 2020
Bauer, R., Conzelmann, C., Forssmann, W., Gačanin, J., Gerbl, F., Groß, R., Hagemann, B., Kirchhoff, F., Krüger, F., Mankertz, A., Münch, J., Olari, L., Preising, N., Rodríguez, A., Ruiz-Blanco, Y., Rücker-Braun, E., Sanchez-Garcia, E., Santibanez, S., Sauter, D., Spellerberg, B., Stenger, S., Ständker, L., Walther, P., Weil, T., Wiese, S.   +24 more
core   +1 more source

Comparative Enzymatic and Stability Assays Reveal GPLG as an Effective Cathepsin B Cleavable Linker for Tumor-Targeting Drug Conjugates. [PDF]

ACS Omega
Cazzaniga G, Zambra M, Bongiolo S, Prpić H, Fasola E, Arrigoni F, Piarulli U, Gazzola S.   +7 more
europepmc   +1 more source

Cathepsin B-dependent glycolysis contributes to reduced renal uric acid excretion in hyperuricemia. [PDF]

Commun Biol
Lin H, Nie L, Wu D, Zhang D, Peng R, Tao S, Ye Z, Zhu S, Ye M, Xiao J.   +9 more
europepmc   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Platinum(IV) anticancer therapies and cathepsin B: innovative strategies for overcoming resistance in glioblastoma cells. [PDF]

Front Cell Dev Biol
Casali C, Gaiaschi L, Pelloni E, Gola F, Cavallo M, Milanesi G, Ravera M, Biggiogera M, De Luca F, Bottone MG.   +9 more
europepmc   +1 more source