Results 211 to 220 of about 25,778,187 (334)

Targeted, receptor‐mediated delivery of a masked d‐amino acid cell‐penetrating peptide for cell‐specific phototoxicity

The FEBS Journal, EarlyView.
A targeted phototoxic peptide selectively accumulates in cells expressing chemokine‐like receptor 1 (CMKLR1). Phototoxicity of the native peptide is low, but cleavage by lysosomal protease cathepsin B releases a 6‐tetramethylrhodamine (TMR) labeled nona‐ᴅ‐arginine which mediates lysosomal rupture and cell death upon irradiation.
Moritz List, Eva‐Maria Jülke, Annette G. Beck‐Sickinger   +2 more
wiley   +1 more source

Suppression of cathepsin B attenuates myocardial injury via limiting cardiomyocyte apoptosis. [PDF]

Open Med (Wars)
Su R, Sun Z, Chen T, Wu H, Li Z, Tang Z, Zhao J, Xu L.   +7 more
europepmc   +1 more source

CATHEPSIN E GENE IN MOUSE

Biomedical Research, 1998
YONEZAWA, SATOSHI, MASAKI, SHIGEO, HANAI, ATSUKO, ONO, TAKAO, SONTA, SHINICHI, HIRAI, HIROHISA, ICHINOSE, MASAO, MIKI, KAZUMASA, TAKAHASHI, KENJI, KAGEYAMA, TAKASHI   +9 more
openaire   +2 more sources

Phenotypic characterization of Arabidopsis thaliana mutants that alleviate root growth defects in a vitamin B6 biosynthesis mutant

The FEBS Journal, EarlyView.
Vitamin B6 is a critical molecule for plant metabolism and development. Rsr4‐1, a loss‐of‐function mutant in a vitamin B6 biosynthesis gene, has a distinct short root phenotype. Here we describe five novel suppressor mutants with an rsr4‐1 background that have normalized root growth and distinct phenotypic and molecular characteristics, representing a ...
Marcelina Parra, Paige Henning, Clayton Bailes, Sanja Roje, Hanjo Hellmann   +4 more
wiley   +1 more source

Cathepsin B ablation alleviates VSMC phenotypic switching by modulating alternative macrophage polarization through the NLRP3 signaling pathway. [PDF]

Front Cardiovasc Med
Gong Z, Long M, Zhang L, Wang C, Liu W.
europepmc   +1 more source

High‐resolution spatial transcriptomic atlas of mouse soleus muscle: Unveiling single cell and subcellular heterogeneity in health and denervation

The FEBS Journal, EarlyView.
Seq‐Scope maps skeletal muscle transcriptomes at high spatial resolution while preserving histological context, revealing distinct responses of myofibers, neuromuscular junctions, and stromal cells to denervation. This spatial view uncovers fiber type‐specific and localized remodeling across intact muscle tissue.
Jer‐En Hsu, Lloyd Ruiz, Yongha Hwang, Steve D. Guzman, Chun‐Seok Cho, Weiqiu Cheng, Yichen Si, Peter Macpherson, Angelo Anacleto, Qingyang Zhao, Xiaoya Zhao, Mitchell Schrank, Goo Jun, Hyun Min Kang, Myungjin Kim, Susan V. Brooks, Jun Hee Lee   +16 more
wiley   +1 more source

Myokine Cathepsin B as a Key Muscle-Brain Axis Regulator Mediates Treadmill-Running-Induced Hippocampal Neurogenesis and Cognitive Improvement in Mice. [PDF]

Research (Wash D C)
Zhou X, Wang D, Deng H, Guo J, Chen X, Lin Z, Liu B, Zhao R, Gao L, Yin X, Zhang Y, Chen Y, Yang Y, Li Q, Shen Q, Ji J, Ni G.   +16 more
europepmc   +1 more source

Chronic Excessive Exercise Aggravates Apical Periodontitis in Mice

International Endodontic Journal, EarlyView.
ABSTRACT Aim To investigate the effects of overtraining on the development of apical periodontitis (AP) in mice. Methodology Sixty 6‐week‐old male C57BL/6 mice were allocated to six groups: sedentary without AP (SED); sedentary with AP (SED AP); aerobic training without AP (AERO); aerobic training with AP (AERO AP); overtraining without AP (OVER); and ...
Andréia Bosco Boaventura, Rosmeli Daysi Coasaca‐Rivera, Bárbara Roma Mendes, Sandra Lia do Amaral, Adelino Sanchez Ramos da Silva, Paulo Sergio Cerri, Gisele Faria   +6 more
wiley   +1 more source

RETRACTION: Mechanism of p27 Upregulation Induced by Downregulation of Cathepsin B and Upar in Glioma. [PDF]

Mol Oncol
europepmc   +1 more source

The mycotoxin Beauvericin is an uncompetitive inhibitor of Cathepsin B. [PDF]

Protein Sci
Yang X, Cea-Medina P, Gopalswamy M, Vaidya A, Schavier S, Oltzen S, Moßner S, Huang A, Qi J, Hölken JM, Teusch N, Floss DM, Uhrberg M, Gohlke H, Scheu S.   +14 more
europepmc   +1 more source