Results 71 to 80 of about 537,647 (300)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Objective aesthetic criteria are important for patient evaluation and analysis during aesthetic surgeries, while successful aesthetic surgeries must take into account the underlying ethnic differences.
Y. Gao +4 more
doaj +1 more source
Role Strain of Nursing Students in Obstetrical Clinical Rotations: Is Role Strain Greater for Male Students? [PDF]
As increasing numbers of men enter the career of nursing, it is important that nursing educators identify areas of role strain and learning needs that may be different from their female counterparts This research project examined the role strain factors ...
Lind, Teri A.
core +1 more source
Negative effects of makeup use on perceptions of leadership ability across two ethnicities [PDF]
Cosmetics alter social perceptions, and prior work suggests that cosmetic use may aid female intrasexual competition, making women appear more dominant to other women but more prestigious to other men. It is unclear whether these findings reflect general
James, Esther A. +2 more
core +2 more sources
Genome‐Wide Association Study of Radiographic Knee Osteoarthritis in North American Caucasians [PDF]
ObjectiveA major barrier to genetic studies of osteoarthritis (OA) is the need to obtain large numbers of individuals with standardized radiographic evaluations for OA. To address this gap, we performed a genome‐wide association study (GWAS) of radiographically defined tibiofemoral knee OA in 3,898 cases and 3,168 controls from 4 well‐characterized ...
Yau, Michelle S +14 more
openaire +6 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Amalgamated reference data for size-adjusted bone densitometry measurements in 3598 children and young adults – the ALPHABET study [PDF]
The increasing use of dual energy X-ray absorptiometry (DXA) in children has led to the need for robust reference data for interpretation of scans in daily clinical practice.
Adams, J.E. +12 more
core +5 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
By considering the expansion of the timber trade in southeast Europe as a resource frontier, this article explores the relationships between the transformation of the technical and material conditions of forest exploitation and the development of its ...
Daheur Jawad
doaj +1 more source

