Results 81 to 90 of about 537,647 (300)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath +7 morewiley +1 more sourceCell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten +5 morewiley +1 more sourceImpact of safety-related dose reductions or discontinuations on sustained virologic response in HCV-infected patients: Results from the GUARD-C Cohort [PDF]
, 2016 BACKGROUND:
Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings.Abbas, Zaigham, Abdou, Ahmed Mohamed Saleh, Abou Rached, Antoine, Acalovschi, Monica, Afredj, Nawel, Ahlers, Silke, Ahmetagic, Sead, Ahn, Sang Hoon, Aissaoui, Magda, Akriviades, Euaggelos, Al Ghandoor, Zuhal, Al Gharabally, Abeer, Al Qameesh, Jihad, Alavian, Seyed Moayed, Alberto, Sara, Aleixo, Maria Jo\ue3o, Amedea, Alessandri, Amoroso, Pietro, Ancuta, Ioan, Andreica, Vasile, Andreoni, Massimo, Arama, Victoria, Ascione, Antonio, Askar, Haifa, Assene, Collins, Attili, Adolfo Francesco, Augustyniak, Krystyna, Baka Cwierz, Barbara, Bakalos, Georgios, Bandiera, Franco, Banyai, Tivadar, Basho, Jovan, Bassi, Paolo, Bastens, Boris, Bellantani, Stefano, Bellati, Giorgio, Berak, Hanna, Bevanda, Milenko, Bhalla, Ajay, Biglino, Alberto, Bocakova, Jana, Bourgeois, Stefan, Brixko, Christian, Brunetto, Maurizia, Bruno, Savino, Bunganic, Ivan, Calkic, Lejla, Caruntu, Florin, Casinelli, Katia, Castellacci, Roberto, Castelli, Francesco, Cattelan, Anna Maria, Chiriaco, Piergiorgio, Cijevschi, Cristina, Colletta, Cosimo, Colombo, Massimo, Colombo, Silvia, Coman, Felicia, Cool, Mike, Coppola, Carmine, Correa, Maria Cassia, Costa, Chiara, Craxi, Antonio, Curescu, Manuela, D'Amico, Emilio, D'Angelo, Salvatore, Daryani, Nasser Ebrahimi, De Galocsy, Chantal, Debzi, Nabil, Decaestecker, Jochen, Delic, Dragan, Delwaide, Jean, Demelia, Luigi, Derbala, Moutaz, Deron, Zbigniew, Di Giacomo, Antonio, Di Perri, Giovanni, Dimitroulopoulos, Dimitrios, Dohaibi, Ahmad, Drakoulis, Christos, Drenaggi, Davide, Elefsiniotis, Ioannis, Enyedi, Judit, Erne, Elke, Esmat, Gamal, Evgenidis, Nikolaos, Fabri, Milotka, Faria, Telo, Ferenci, Peter, Fernandes, Julio Cesar, Ferrari, Carlo, Ferraz, Maria Lucia, Fierbinteanu Braticevici, Carmen, Flisiak, Robert, Foster, Graham R., Foti, Giuseppe, Francisci, Daniela, Fried, Katalin, Gabr, Mamdouh, Ganga, Roberto, George, Christophe, Gervain, Judit, Gheorghe, Liana, Giannoulis, Grigoris, Gietka, Andrzej, Giguere, Alain, Gomide, Geisa, Guerreiro, Hor\ue1cio, Guessab, Nawal, Halota, Waldemar, Han, Sang Young, Hanno, Abdelfatah, Harxhi, Arjan, Hashmi, Zahid, Hassanein, Tarek, Hausinger, P\ue9ter, Henrion, Jean, Holoman, Jozef, Horsmans, Yves, Hoste, Paul, Houmani, Zaher, Hunyady, Bela, Ibrahimpasic, Nevzeta, Ionita Radu, Florentina, Ivanovski, Ljubomir, Jablkowski, Maciej, Jankovic, Goran, Janssens, Filip, Jarcuska, Peter, Jesic, Rada, Joksimovic, Nenad, Junior, Elson Martins, Juriens, Ir\ue8ne, Kanatakis, Stilianos, Karagiannis, Ioannis, Karatapanis, Stilianos, Ketikoglou, Ioannis, Kim, Yoonjun, Konstantinovic, Ljiljana, Krkoska, Dusan, Kupcova, Viera, Lakner, Lilla, Langlet, Philippe, Lasser, Luc, Laukens, Pierre, Lawate, Parimal, Lee, Yun Nah, Lefebvre, Veronique, Lencu, Monica, Lengyel, Gabriella, Lesch, Miklos, Lipczynski, Artur, Livia, Hara, Luaia, Rosang, Lyra, Andre, Macedo, Guilherme, Mahindad, Nadir, Mahiou, Hassene, Makkai, Erzs\ue9bet, Malhado, Jos\ue9, Manesis, Emmanuel, Mangia, Alessandra, Manolakopoulos, Spilios, Mansinho, Kamal, Martinet, Jean Paul, Masood, Siddiq, Matarazzo, Filippo, Mazur, Wlodzimierz, Mazzella, Giuseppe, Mazzeo, Maurizio, Megna, Angelo Salomone, Mela, Maria, Mello, Carlos Eduardo, Memoli, Massimo, Memon, Sadik, Mendes, Claudio, Merat, Shahin, Mesihovic, Rusmir, Michielsen, Peter, Miftode, Egidia, Mimidis, Konstantinos, Mohsin, Aftab, Montalbano, Marzia, Montalto, Giuseppe, Monteverde, Carlos, Motoc, Adriana, Mousoulis, Georgios, Mulkay, Jean Pierre, Musat, Marioara, Musialik, Joanna, Nagorni, Aleksandar, Nagral, Aabha, Nagy, Istvan, Nassiri Toosi, Mohsen, Nemes\ue1nszky, Elem\ue9r, Nevens, Frederik, Nikolopoulou, Vassiliki, Nozic, Darko, Olszok, Iwona, Olteanu, Dan, Oltman, Marian, Omar, Ashraf, Orfanou, Eleni, Orlandini, Alessandra, Orszulak, Grazyna, Ozsv\ue1r, Zs\uf3fia, Paik, Seung Woon, Parikh, Samir, Pascu, Oliviu, Passariello, Nicola, Patai, \uc1rp\ue1d, Peixe, Paula, Pelemis, Mijomir, Pereira, Patricia, Philip, Mathew, Picciotto, Antonio, Piekarska, Anna, Piekos, Tomasz, Pieri, Alessandro, Pietrangelo, Antonello, Pigozzi, Maria Graziella, Pirisi, Mario, Preotescu, Liliana, Quirino, Tiziana, Racz, Istvan, Radowska, Danuta, Raimondo, Giovanni, Ramos, Jos\ue9 Presa, Rao, Padaki, Rapaccini, Gian Ludovico, Reddy, K. Rajender, Reynaert, Hendrik, Ribiczey, P\ue1l, Rizzardini, Giuliano, Rizzetto, Mario, Robaeys, Geert, Roxo, Fausto, Ruiz, Fernando Jose, Russello, Maurizio, Russo, FRANCESCO PAOLO, Sabusco, Giuseppe, Santantonio, Teresa, Saracco, Giorgio Maria, Sarmento Castro, Rui, Schneider, Ferenc, Schreter, Ivan, Schuller, J\ue1nos, Serejo, F\ue1tima, Servais, Benoit, Shabanaj, Gentian, Sharara, Ala, Shiffman, Mitchell L., Sieklucki, Jerzy, Silaghi, Rodica, Silva, Giovanni, Silva, Mariliza Henrique, Simon, Krzysztof, Skladany, Lubomir, Soardo, Giorgio, Somani, Sanjay, Sood, Ajit, Spinzi, Giancarlo, Sporea, Ioan, Sprengers, Dirk, Stan, Marioara, Stanciu, Carol, Streinu Cercel, Adrian, Svorcan, Petar, Szalay, Ferenc, Szantova, Maria, Szentgy\uf6rgyi, L\ue1szl\uf3, Szlauer, Bronislawa, Tallarico, Ludovico, Teixeira, Rosangela, Todorovic, Zoran, Tolvaj, Gyula, Tornai, Istvan, Trifan, Anca, Tsianos, Epameinondas, Tundo, Paolo, Tusnadi, Anna, V\ue1czi, Zsuzsanna, Vafiadi Zoubouli, Irini, Valente, Cristina, Van Der Meersch, Filip, Van Vlierberghe, Hans, Varga, Marta, Varghese, Rosh, Varkonyi, Istvan, Velez, Jorge, Verhaz, Antonija, Verucchi, Gabriella, Vinci, Maria, Vincze, Aron, Vinelli, Francesco, Warakomska, Iwona, Warzee, Philippe, Yaghi, Cesar, Yang, Jinmo, Yousry, Ayman, Zaarour, Fouad, Zali, Mohammad Reza, Zignego, Anna Linda, Zuin, Massimo +303 morecore +1 more sourceTransferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti +9 morewiley +1 more sourceIdentification of the Kna/Knb polymorphism and a method for Knops genotyping [PDF]
, 2004 BACKGROUND: DNA mutations resulting in the McCoy and Swain-Langley polymorphisms have been identified on complement receptor 1 (CR1)—a ligand for rosetting of Plasmodium falciparum-infected RBCs.Daniels, Helgeson, Krych-Goldberg, Mallan, Molthan, Molthan, Moulds, Moulds, Moulds, Moulds, Moulds, Moulds, Moulds, Moulds, Rao, Rowe, Tamasauskas, Zimmerman +17 morecore +1 more sourceTau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido +3 morewiley +1 more source
