Results 41 to 50 of about 578,888 (312)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Pre-emptive caudal epidural analgesia with ropivacaine for lumbosacral spine surgery: A randomized case control study

open access: yesJournal of Anaesthesiology Clinical Pharmacology, 2018
Background and Aims: Pre-emptive analgesia using caudal epidural technique is an underutilized technique in lumbosacral spine surgery patients. We intend to study if pre-emptive analgesia with a single caudal epidural injection of ropivacaine is an ...
Navneh Samagh   +4 more
doaj   +1 more source

T-cadherin expression alternates with migrating neural crest cells in the trunk of the avian embryo [PDF]

open access: yes, 1991
Trunk neural crest cells and motor axons move in a segmental fashion through the rostral (anterior) half of each somitic sclerotome, avoiding the caudal (posterior) half.
Bronner-Fraser, Marianne   +1 more
core  

Hesperiidae of Rondônia, Brazil: Porphyrogenes Watson (Lepidoptera: Pyrginae: Eudamini), with descriptions of new species from Central and South America [PDF]

open access: yes, 2008
The pyrgine genus Porphyrogenes Watson, 1893 (Hesperiidae) is discussed, especially as it occurs in central Rondônia, Brazil. Of eleven species of Porphyrogenes found in Rondônia, four (P. specularis, P. convexus, P. sparus, and P.
Austin, George T.   +1 more
core   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas   +39 more
wiley   +1 more source

A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome. [PDF]

open access: yes, 2018
The aim of our study was to limit the inflammatory response after a spinal cord injury (SCI) using Atorvastatin (ATR), a potent inhibitor of cholesterol biosynthesis.
Bacova, Maria   +11 more
core   +2 more sources

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

Variables meteorológicas y desarrollo fenológico de la caña de azúcar en Aguada de Pasajeros

open access: yesRevista Cubana de Meteorología, 2019
La investigación se realizó en el terreno de observación No. 1 de la Estación Agrometeorológica Aguada de Pasajeros con el objetivo de determinar la influencia de variables meteorológicas sobre el desarrollo fenológico de la caña de azúcar. Se utilizaron
Marlene Ramírez-Gonzáles   +3 more
doaj  

Recursos hídricos superficiales de la vertiente oriental de los Andes Centrales (28°-37°S) en contexto de variabilidad hidroclimática

open access: yesBoletín de Estudios Geográficos, 2021
El estudio de la variabilidad hidroclimática de una región contribuye a mejorar la seguridad hídrica de las comunidades ya que brinda información para la gestión de los recursos hídricos.
Carolina Lauro   +5 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

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