Results 71 to 80 of about 39,218 (259)

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source

Nacre‐inspired layered composite with excellent mechanical support and osteogenic potential for cervical interbody cage

BMEMat, EarlyView.
The cervical interbody cage needs to take both biomechanical and biological requirements into account. Here, a new‐style degradable, multicomponent, and bioinspired nacre‐like cervical interbody cage composite, which exhibits promising mechanical‐support‐related behavior and osteogenesis‐related potential, is designed and prepared.
Xiu‐Wu Guo, Shao‐Meng Wen, Tian‐Yu Xing, Yang Zhou, Chun‐Xin Wang, Chang Ge, Si‐Ming Chen, Wen‐Zhi Zhang, Shu‐Hong Yu   +8 more
wiley   +1 more source

Variations in Human Trigeminal and Facial Nerve Branches and Foramina Identified by Dissection and Microcomputed Tomography

Clinical Anatomy, EarlyView.
ABSTRACT The aim of this study was to identify branches of the trigeminal and facial nerves (FNs) relevant to surgical incisions and injections and the scalp block techniques in the frontotemporal region, and to determine their relationships with superficial vascular structures and bony landmarks.
Hannah L. Grimes, Valentina Pizzuti, Maria A. Wright, Kane P. J. Colston, Thomas Santarius, Susan Jones   +5 more
wiley   +1 more source

Caudal anesthesia for anoplasty in a toddler with uncorrected tetralogy of Fallot: a case report

Патология кровообращения и кардиохирургия
Background: Non-cardiac surgery is prevalent among individuals with a history of cyanotic congenital heart disease (CHD), including tetralogy of Fallot (ToF). Surgical and anesthetic procedures in such patients may lead to multiple complications.
Dini Meta Rica, Kohar Hari Santoso, Ferriansyah Gunawan   +2 more
doaj   +1 more source

A Randomized Controlled Trial Comparing the TruSteer and FXD Double Curve Delivery Systems for Left Atrial Appendage Occlusion With the Watchman FLX Pro Device—The GUIDE‐LAAO Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Deflectable delivery systems have been introduced to enhance coaxial alignment and procedural efficacy during left atrial appendage occlusion (LAAO), yet randomized comparisons with conventional fixed‐curve systems are lacking. Aims The GUIDE‐LAAO trial evaluated whether the TruSteer deflectable delivery system is non‐inferior to ...
Philippe Taieb, Marco Frazzetto, Pedro Soares Teixeira, Steven J. Filby   +3 more
wiley   +1 more source

A comparative study of the effect of caudal dexmedetomidine versus morphine added to bupivacaine in pediatric infra-umbilical surgery

Saudi Journal of Anaesthesia, 2014
Background: One of the most commonly used regional anesthetic techniques in pediatric surgeries is the caudal epidural block. Its main disadvantage remains the short duration of action. Hence, different additives have been used.
Hossam A El Shamaa, Mohamed Ibrahim
doaj   +1 more source

Zebrafish inversin mutants develop scoliosis in the absence of laterality defects

Developmental Dynamics, EarlyView.
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick, Lorraine Eley, Deborah J. Henderson, Bill Chaudhry   +3 more
wiley   +1 more source

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Using the adjuvants during infusion of local anaestetics into caudal-epidural space in newborns

Patologìâ, 2012
Markers of stress and central haemodynamics were investigated in 45 newborns. General anesthesia and caudal infusion of local anesthetics were combined in 15 newborns. Promedol and clonidine were added to local anesthetics in 15 newborns.
M. Yu. Kurochkin
doaj   +1 more source