Results 171 to 180 of about 9,491,507 (312)

Potential Causal Association Between Plasma Lipidomes and Keloid: Analysis from a Two-Sample Mendelian Randomization. [PDF]

Clin Cosmet Investig Dermatol
Ma T, Wu H, Gong S.
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Comment on: Causal association between sleep phenotypes and susceptibility to childhood asthma: A two-sample Mendelian randomization study. [PDF]

Pediatr Allergy Immunol
Dan Q.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Causal association between sleep phenotypes and susceptibility to childhood asthma: A two-sample Mendelian randomization study. [PDF]

Pediatr Allergy Immunol
Yin L, Zhang F, Li F, Gao M, Liu A, Wang X.   +5 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Causal association between rheumatoid arthritis and periodontitis: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Li X, Ouyang Y, Liang L, Li Y.
europepmc   +1 more source

Proceedings of the Joint Conference of the American Library Association - Canadian Library Association

, 1960
The joint conference proceedings from the 1960 American Library Association and Canadian Library Association Conference at Montreal, Quebec, June 19 ...
American Library Association, Canadian Library Association   +1 more
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Causal association between tobacco use, fibroblast growth factors, and pulmonary fibrosis: A two-sample Mendelian randomization study. [PDF]

Tob Induc Dis
Yu R, Han X, Wang M, Sun Y.
europepmc   +1 more source