Results 41 to 50 of about 1,284,492 (275)

Description of variables used in causal loop diagrams.

open access: yes, 2020
Description of variables used in causal loop diagrams.
Nicos Maglaveras (8537733)   +6 more
core   +1 more source

A qualitative system dynamics perspective on the contribution of information technology credibility towards business and information technology alignment

open access: yesSouth African Journal of Business Management, 2022
Purpose: The dynamic interdependence between the deployment of technological assets and organisational performance remains a challenge for modern enterprises.
Martin J. Butler
doaj   +1 more source

EVALUATING POLICY INSTRUMENT COMPLEXITY WITH CAUSAL LOOP DIAGRAMS

open access: yes, 2023
Methods to capture the complexity of using policy instruments would allow us to better evaluate the reasons for their effectiveness. Drawing from complexity science, we produce a Causal Loop Diagram to analyse the implementation of two informational policy instruments in a tourism destination: the Global Sustainable Tourism Council criteria and the ...
Gloria Crabolu, Xavier Font, Sibel Eker
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Building food system resilience: insights from Finland using causal loop diagrams

open access: yesEcology and Society
The resilience of European food systems is being put to the test by complex and unexpected shocks, disruptions, and discontinuities, recent examples of which include COVID‑19 and the Russian invasion of Ukraine. Owing to the complexity of the food system
Pasi Rikkonen   +3 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

How do participatory methods shape policy? Applying a realist approach to the formulation of a new tuberculosis policy in Georgia

open access: yesBMJ Open, 2021
Objectives This paper presents the iterative process of participatory multistakeholder engagement that informed the development of a new national tuberculosis (TB) policy in Georgia, and the lessons learnt.Methods Guided by realist evaluation methods, a ...
Sophie Witter   +10 more
doaj   +1 more source

The Dynamics of Concussion: Mapping Pathophysiology, Persistence, and Recovery With Causal-Loop Diagramming [PDF]

open access: yesFrontiers in Neurology, 2018
Despite increasing public awareness and a growing body of literature on the subject of concussion, or mild traumatic brain injury, an urgent need still exists for reliable diagnostic measures, clinical care guidelines, and effective treatments for the condition.
Erin S. Kenzie   +9 more
openaire   +4 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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