Results 51 to 60 of about 1,284,492 (275)
Frontiers in SustainabilityIntroductionThis study employed a systems thinking approach to explore the complex and dynamic interactions between sustainability initiatives, and employees' subsequent perceptions, attitudes, and behaviors.
Carolina Bettker Vasconcelos +3 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Catalogue of rebound mechanisms represented in causal loop diagrams
, 2023 This dataset includes the catalogue of 26 rebound mechanisms, i.e., structures leading to rebound effects (RE), based on qualitative system dynamics (SD) modelling using causal loop diagrams (CLD) identified in the literature.It is the supplementary data
Daniel Guzzo (11995046) +4 more
core +2 more sources
BMC Public Health, 2020 Background Tobacco and alcohol use are major behavioural risks in developing countries like Nepal, which are contributing to a rapid increase in non-communicable diseases (NCDs).
Sudesh Raj Sharma +6 more
doaj +1 more source
Understanding social innovation in local energy transitions processes: A multi-case study
Global Transitions, 2021 Social innovation (SI) in local energy transitions is gaining focus in current times but energy transitions have not yet been explicitly analysed in the context of SI.
Sujeetha Selvakkumaran, Erik O. Ahlgren
doaj +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Systems Thinking with Causal Loop Diagrams in Medical Education: An Exploratory Study
SystemsMedical literature is replete with diagrammatic representations of systems, yet lacks standardised nomenclature and consistent symbolic conventions. In an introductory system dynamics course for health science students, causal loop diagrams (CLDs) are ...
David M. Rubin +4 more
doaj +1 more source
Qualitative Causal Loop Diagram: One Health Model Conceptualizing Brucellosis in Jordan
Systems, 2023 Background: Brucellosis is a serious public health problem distributed worldwide. Jordan has one of the highest incidences of brucellosis globally, mostly caused by infection with Brucella melitensis, which is associated with small, ruminant animals such as sheep.
Haitham Taha +3 more
openaire +5 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Characterizing Communication Channel Deadlocks in Sequence Diagrams [PDF]
, 2008 UML sequence diagrams (SDs) are a mainstay of requirements specifications for communication protocols. Mauw and Reniers' algebraic (MRA) semantics formally specifies a behaviour for these SDs that guarantees deadlock free processes.
Mitchell, Bill, B. Mitchell
core +2 more sources