Results 81 to 90 of about 5,363 (277)
The integrated use of enterprise and system dynamics modelling techniques in support of business decisions [PDF]
, 2012 Enterprise modelling techniques support business process re-engineering by capturing existing processes and based on perceived outputs, support the design of future process models capable of meeting enterprise requirements.
Ratchev, Svetan +2 more
core +1 more source
Using causal loop diagrams to explore behavioural and socio-technical safety challenges [PDF]
, 2023 In 2021, the EI published a Research report: Achieving greater resilience to major events – Organisational learning for safety risk management in complex environments, which identified common contributory organisational and cultural deficiencies that led
May, John H R +4 more
core +2 more sources
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Learning to track systems change using causal loop diagrams
, 2023 Learning to track systems change using causal loop ...
Brynle Owen (767358) +9 more
core
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Patterns of systemic problems in Ghana's poultry value chain: A group model building approach
Journal of Agriculture and Food ResearchGhana's poultry sector faces different interrelated systemic challenges, often diagnosed in isolation, leading to interventions that neglect unintended consequences across the value chain.
Joshua Aboah +5 more
doaj +1 more source
Environmental and Climate Technologies, 2015 A participatory system dynamics modelling approach is advanced to support conceptualization of feedback processes underlying ecosystem services and to foster a shared understanding of leverage intervention points.
Lopes Rita, Videira Nuno
doaj +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Adaptation Behavior of Mango Farmers to Climate Change
Jurnal Manajemen & Agribisnis, 2018 The continuing climate change phenomenon causes disruption to agricultural sector including seasonal fruits such as mangoes. To anticipate the negative effects of climate change, the farmers adapt themselves in order to maintain their mango farming.
Dhany Esperanza +4 more
doaj +1 more source